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TOPIRAMATE
SynDRA canonical compound SYN0006487 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | CA4 |
|---|
| Mechanism of action | Glutamate receptor antagonist |
|---|
| Indication | epilepsy | migraine headache |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- GRIK1
- SCN1A
- SCN5A
- CA2
- CA4
- GABRG2
- GABRA1
- GABRB2
- GRIA1
- GRIA4
- GRIA3
- GRIA2
Mechanisms of action (all sources)
- Kainate receptor antagonist
- Carbonic anhydrase inhibitor
- Glutamate receptor antagonist
- CA2 INHIBITOR
- Carbonic anhydrase II inhibitor
- CA4 INHIBITOR
- Carbonic anhydrase IV inhibitor
- SCN1A BLOCKER
- Sodium channel alpha subunit blocker
- SCN5A BLOCKER
- SCN4A BLOCKER
- SCN7A BLOCKER
Drug classes
- Anticonvulsants
- Central Nervous System Agents
- Hypoglycemic Agents
- Cytochrome P450 2C19 Inhibitors
- Cytochrome P450 3A4 Inducers
ATC classes
- N03A · ANTIEPILEPTICS
- ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS
Cross-references
Synonyms
- beta-D-fructopyranose sulfamate
- epitoma
- epitomax
- topamac
- topamax
- topimax
- topomax
- topina
- Topiramato
- (-)-topiramate
- Epitoma
- Eprontia
- Qudexy
- Sincronil
- Topamac
- Topimax
- Topina
- Topomax
- MCN-4853
- RWJ-17021
- RWJ-17021-000
- USL-255
- USL255
- Epitomax
- Qudexy xr
- Topamax
- Topamax sprinkle
- Topiramate component of qsymia
- Trokendi xr
- TOR
- Tipiramate
- Tipiramato
- Topiramatum
- Cilag brandof topiramate
- Janssen brand of topiramate
- Ortho brand of topiramate
- Tipiramate [French]
- Tipiramato [Spanish]
Reported adverse events
- Fatigue
- Depression
- Vertigo
- Alopecia
- Myopia
- Nausea
- Somnolence
- Dizziness
- Hyperthermia
- Agitation
- Anxiety
- Asthenia
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