← SynDRA

TOFACITINIB

SynDRA canonical compound SYN0006517 — structure-anchored drug synonym record

All known targets

• JAK3
• JAK2
• JAK1
• TYK2
• ABL1
• ROCK1
• PKN1
• PKN2
• PRKCA
• PRKCD
• RET
• ROCK2

Mechanisms of action (all sources)

• JAK inhibitor
• JAK3 INHIBITOR
• Janus Kinase (JAK) inhibitor
• JAK1 INHIBITOR
• JAK2 INHIBITOR
• TYK2 INHIBITOR
• JAK3 MODULATOR

Drug classes

• Enzyme Inhibitors
• Janus Kinase Inhibitors
• Protein Kinase Inhibitors
• Janus Kinase Inhibitor

ATC classes

• L04A · IMMUNOSUPPRESSANTS

Cross-references

• PubChem CID: 9926791
• ChEMBL: CHEMBL221959
• DrugBank: DB08895
• ChEBI: CHEBI:71200
• KEGG: D09783
• RxNorm: 1357536
• PDB: MI1
• Wikipedia: Tofacitinib
• TTD: D0EG1I
• LINCS BRD: BRD-K31283835

Synonyms

• tasocitinib
• xeljanz
• CP-690550
• tofacitinib citrate
• CP-690 FREE BASE
• 550
• CP-690-550
• CP-690
• CP-690,550
• CP-690,550 FREE BASE
• CP-690550 FREE BASE
• CP-690550-10
• CP690,550
• CP690550
• PFE-PKIS 25
• PFE-PKIS_25
• TASOCITINIB
• TASOCITINIB CITRATE
• TOFACITINIB (CONTROLLED RELEASE)
• TOFACITINIB (CP-690550)
• Tofacitinib citrate
• Xeljanz
• Tasocitinib
• 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
• CP 690550
• racemic-tofacitinib
• tofacitinibum
• UNII-87LA6FU830
• 3-((3R,4R)-rel-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
• 3-{(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}-3-oxopropanenitrile
• Tofacitinib (CP-690550,Tasocitinib)
• CHEMBL221959
• CHEBI:71200
• Xeljanz (TN)
• Cp-690 free base
• CP- 690 550
• (+)-TOFACITINIB
• cp-690,550