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FLUOROURACIL

SynDRA canonical compound SYN0006605 — structure-anchored drug synonym record

All known targets

• TYMS
• DPYD
• ABCC11
• ABCC5
• CD44
• CYP19A1
• Candi TMP1
• TERT
• upp

Mechanisms of action (all sources)

• RNA synthesis inhibitor
• thymidylate synthase inhibitor
• TYMS INHIBITOR
• Inhibitor
• DPYD INHIBITOR

Drug classes

• Nucleic Acid Synthesis Inhibitors
• Antimetabolites
• Antimetabolites, Antineoplastic
• Antineoplastic Agents
• Immunologic Factors
• Immunosuppressive Agents
• Noxae
• Nucleoside Metabolic Inhibitor

ATC classes

• L01B · ANTIMETABOLITES

Cross-references

• PubChem CID: 3385
• ChEMBL: CHEMBL185
• DrugBank: DB00544
• ChEBI: CHEBI:46345
• KEGG: D00584
• RxNorm: 4492
• PDB: URF
• Wikipedia: Fluorouracil
• TTD: D05LEO
• LINCS BRD: BRD-K24844714

Synonyms

• 5-fluorouracil
• adrucil
• fluoroblastin
• 5-FU
• Fluorouracilo
• 5-fluoruracil
• Fluorouracilum
• Fluorouricil
• Fluracil
• Phthoruracil
• Queroplex
• NSC-19893
• RO-2-9757
• RO-29757
• 5.f.u.
• Accusite
• Actikerall
• Adrucil
• Carac
• Efudex
• Efudix
• Fluoro-uracil roche
• Fluoroplex
• Fluorouracil component of folfox
• Tolak
• 5 Fluorouracil
• Fluoroblastin
• 5-fluoropyrimidine-2,4(1H,3H)-dione
• Kecimeton
• Timazin
• Carzonal
• Arumel
• Fluril
• Fluracilum
• Ulup
• 5-Fluoracil
• Fluro Uracil
• 5-Fluoro-2,4(1H,3H)-pyrimidinedione

Reported adverse events

• Death
• Myelosuppression
• Cardiotoxicity
• Alopecia
• Eosinophilia
• Herpes simplex
• Leukocytosis
• Ulcer
• Hypersensitivity
• Erythema
• Infection
• Eye swelling