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METFORMIN
SynDRA canonical compound SYN0006629 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | ACACB | INS | PRKAB1 |
|---|
| Mechanism of action | insulin sensitizer |
|---|
| Indication | diabetes mellitus |
|---|
| Disease area | endocrinology |
|---|
All known targets
- ACACB
- NDUFC2
- NDUFB1
- NDUFB10
- NDUFB11
- NDUFB2
- NDUFB3
- NDUFB4
- NDUFB5
- NDUFB6
- NDUFB7
- NDUFB8
Mechanisms of action (all sources)
- MT-ND6 INHIBITOR
- Mitochondrial complex I (NADH dehydrogenase) inhibitor
- NDUFA10 INHIBITOR
- NDUFS8 INHIBITOR
- MT-ND4L INHIBITOR
- NDUFA6 INHIBITOR
- MT-ND1 INHIBITOR
- NDUFB6 INHIBITOR
- COXFA4 INHIBITOR
- NDUFA11 INHIBITOR
- NDUFB7 INHIBITOR
- MT-ND2 INHIBITOR
Drug classes
- Biguanide
- Hypoglycemic Agents
ATC classes
- A10B · BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
Cross-references
Synonyms
- metformin hydrochloride
- glucophage
- LA 6023
- N,N-dimethylguanylguanidine
- metformin HCl
- Metformine
- Metformina
- Metformin extended release
- LA-6023
- 1,1-Dimethylbiguanide
- N,N-dimethylimidodicarbonimidic diamide
- Metiguanide
- Dimethylbiguanide
- Glucophage
- Haurymelin
- Gliguanid
- Fluamine
- Glumetza
- Flumamine
- Melbin
- Diabex
- N,N-Dimethylbiguanide
- Metforminum
- Islotin
- Glifage
- Siofor
- N1,N1-Dimethylbiguanide
- DMGG
- NNDG
- Dimethyldiguanide
- N,N-Dimethyldiguanide
- Metformina [DCIT]
- Imidodicarbonimidic diamide, N,N-dimethyl-
- Metformina [Spanish]
- Metforminum [INN-Latin]
- Metformine [INN-French]
- Metformin [USAN:INN:BAN]
- 1,1-Dimethyl
Reported adverse events
- Lactic acidosis
- Lactic acid
- Metformin associated lactic acidosis
- Nausea
- Headache
- Vomiting
- Flatulence
- Asthenia
- Abdominal pain
- Dizziness
- Angioedema
- Hypersensitivity
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