RALTITREXED

SynDRA canonical compound SYN0006800 — structure-anchored drug synonym record

Clinical phase	Launched
Primary target(s)	TYMS
Mechanism of action	Thymidylate synthase inhibitor
Indication	mesothelioma
Disease area	oncology

All known targets

tomudex
D-1694
ICI-D1694
ZD-1694
ZD-16
ZD1694
Tomudex
ZD 1694
ICI D1694
D 1694
UNII-FCB9EGG971
D1694
CHEBI:5847
Raltitrexed (Tomudex)
C21H22N4O6S
(2S)-2-[[5-[methyl-[(2-methyl-4-oxo-1H-quinazolin-6-yl)methyl]amino]thiophene-2-carbonyl]amino]pentanedioic acid
FCB9EGG971
CHEMBL225071
N-(5-(N-(3,4-Dihydro-2-methyl-4-oxoquinazolin-6-ylmethyl)-N-methylamino)-2-thenoyl)-L-glutamic acid
ICI-D-1694
NSC-639186
NCGC00229704-01
DSSTox_RID_81653
DSSTox_CID_26482
DSSTox_GSID_46482
N-(5-(((3,4-Dihydro-2-methyl-4-oxo-6-quinazolinyl)methyl)methylamino)-2-thenoyl)-L-glutamic acid
(2S)-2-[(5-{methyl[(2-methyl-4-oxo-1,4-dihydroquinazolin-6-yl)methyl]amino}thiophen-2-yl)formamido]pentanedioic acid
(S)-2-(5-(Methyl((2-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)-methyl)amino)thiophene-2-carboxamido)pentanedioic acid
(S)-2-(5-(methyl((2-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)methyl)amino)thiophene-2-carboxamido)pentanedioic acid
L-Glutamic acid, N-((5-(((1,4-dihydro-2-methyl-4-oxo-6-quinazolinyl)methyl)methylamino)-2-thienyl)carbonyl)-
N-(5-[N-(3,4-dihydro-2-methyl-4-oxoquinazolin-6-ylmethyl)-N-methylamino]-2-thenoyl)-L-glutamic acid
(2S)-2-[[5-[methyl-[(2-methyl-4-oxo-3H-quinazolin-6-yl)methyl]amino]thiophene-2-carbonyl]amino]pentanedioic acid
D16
Tomudex (TN)
CAS-112887-68-0
Raltitrexed (JAN/USAN/INN)
1hvy
2kce