PEMETREXED

SynDRA canonical compound SYN0006801 — structure-anchored drug synonym record

Clinical phase	Launched
Approval status	Approved · Rx/OTC
Primary target(s)	TYMS
Mechanism of action	Dihydrofolate reductase inhibitor
Indication	mesothelioma \| non-small cell lung cancer (NSCLC)
Disease area	oncology

All known targets

LY231514
pemetrexed diacid monohydrate
pemetrexed sodium
pemetrexed sodium hydrate
pemetrexed disodium
alimta
pemetrexed disodium heptahydrate
LY-231514
NSC-698037
Alimta
Pemfexy
LYA
Alimta (TN)
LY-231,514
LY-2315
Pemetrexed (INN)
Pemetrexed [INN:BAN]
N-(4-(2-(2-Amino-3,4-dihydro-4-oxo-7H-pyrrolo(2,3-d)pyrimdin-5-yl)ethyl)benzoyl)glutamic acid
N-{4-[2-(2-amino-4-oxo-4,7-dihydro-1h-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}-d-glutamic acid
(2R)-2-[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid
(2S)-2-[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid
2-[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid
2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-PENTANEDIOIC ACID
LY 231514
PEMFEXY
CHEBI:63616
Pemetrexed Sodium
pemetrexedum
AXTLE
Multitargeted Antifolate
RefChem:6105
PEMETREXED FOR INJECTION
DTXCID7028304
LY 231,514
PEMETREXED [INN]
UNII-04Q9AIZ7NO
MFCD19105065
s5971