← SynDRA

LETROZOLE

SynDRA canonical compound SYN0006820 — structure-anchored drug synonym record

All known targets

• CYP19A1
• CYP11B1
• CYP11B2

Mechanisms of action (all sources)

• Aromatase inhibitor
• CYP19A1 INHIBITOR
• Cytochrome P450 19A1 inhibitor

Drug classes

• Aromatase Inhibitors
• Aromatase Inhibitor
• Antineoplastic Agents
• Enzyme Inhibitors
• Estrogen Antagonists
• Hormone Antagonists
• Steroid Synthesis Inhibitors

ATC classes

• L02B · HORMONE ANTAGONISTS AND RELATED AGENTS

Cross-references

• PubChem CID: 3902
• ChEMBL: CHEMBL1444
• DrugBank: DB01006
• ChEBI: CHEBI:6413
• KEGG: D00964
• RxNorm: 72965
• Wikipedia: Letrozole
• TTD: D0C1WH
• LINCS BRD: BRD-K88789588

Synonyms

• CGS 20267
• lerozole
• letrazole
• femara
• Letrozol
• CGS-20267
• NSC-759652
• Femara
• Letrozole component of kisqali femara co-pack
• Femera
• Letoval
• Novartis Brand of Letrozole
• FEM-345
• Femara (TN)
• Letrozole [USAN:INN]
• CGS 20267, Femara, Piroxicam, Letrozole
• Letrozole (JAN/USP/INN)
• 1-[Bis-(4-cyanophenyl)methyl]-1,2,4-triazole
• 1-[bis(4-cyanophenyl)methyl]-1,2,4-triazole
• 4,4'-((1h-1,2,4-triazol-1-yl)methylene)dibenzonitrile
• 4,4'-(1H-1,2,4-Triazol-1-ylmethylene)dibenzonitrile
• 4,4'-(1H-1,2,4-triazol-1-yl-methylene)-bis(benzonitrile)
• 4,4'-(1H-1,2,4-triazol-1-ylmethanediyl)dibenzonitrile
• 4,4'-(1H-1,2,4-triazol-1-ylmethylene)bis-Benzonitrile Letrozole
• 4,4'-(1h-1,2,4-triazol-1-ylmethylene) bis-benzonitrile
• 4,4'-(1h-1,2,4-triazol-1-ylmethylene)bis-benzonitrile
• 4,4'-(1h-1,2,4-triazol-1-ylmethylene)bisbenzonitrile
• 4-[(4-cyanophenyl)-(1,2,4-triazol-1-yl)methyl]benzonitrile
• LETRAZOLE
• Benzonitrile, 4,4'-(1H-1,2,4-triazol-1-ylmethylene)bis-
• NSC 759652
• CHEMBL1444
• 4-[(4-CYANOPHENYL)(1H-1,2,4-TRIAZOL-1-YL)METHYL]BENZONITRILE
• 7LKK855W8I
• CHEBI:6413
• NCGC00016973-01
• CAS-112809-51-5
• SMR000466343

Reported adverse events

• Alopecia
• Fatigue
• Headache
• Infection
• Nausea
• Asthenia
• Cataract
• Constipation
• Cough
• Depression
• Hypertension
• Insomnia