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PRETOMANID
SynDRA canonical compound SYN0007067 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx |
|---|
| Primary target(s) | FASN |
|---|
| Mechanism of action | nitric oxide donor |
|---|
All known targets
- FASN
- MycB cmaA1; MycB cmaA2; MycB pcaA
Mechanisms of action (all sources)
- nitric oxide donor
- Inhibitor
Drug classes
- Antimycobacterial
- Organic Anion Transporter 3 Inhibitors
ATC classes
- J04A · DRUGS FOR TREATMENT OF TUBERCULOSIS
Cross-references
Synonyms
- PA-824
- PA824
- Dovprela (previously pretomanid fgk)
- PA 824
- UNII-2XOI31YC4N
- (S)-PA 824
- (S)-2-Nitro-6-((4-(trifluoromethoxy)benzyl)oxy)-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine
- 2XOI31YC4N
- CHEMBL227875
- MMV688755
- AK161427
- (6S)-2-nitro-6-[[4-(trifluoromethoxy)phenyl]methoxy]-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine
- (6S)-6,7-Dihydro-2-nitro-6-[[4-(trifluoromethoxy)phenyl]methoxy]-5H-imidazo[2,1-b][1,3]oxazine
- Pretomanid [USAN:INN]
- C14H12F3N3O5
- PA-824(Pretomanid)
- AC1L9UFX
- Pretomanid (USAN/INN)
- MLS006011141
- SCHEMBL2983011
- PA824 cpd
- pretomanidum
- RefChem:57158
- DTXCID6021163
- MFCD06809939
- (S)-PA 824 (Pretomanid)
- Pretomanid (Standard)
- PRETOMANID [MI]
- PRETOMANID [INN]
- PA-824(Pretomanid)?
- PRETOMANID [USAN]
- Pretomanid(S)-PA 824
- PRETOMANID [WHO-DD]
- orb1301077
- orb3141401
- PRETOMANID [ORANGE BOOK]
- GTPL11172
- ZLHZLMOSPGACSZ-NSHDSACASA-N
Reported adverse events
- Abdominal pain
- Abnormal loss of weight
- Acne
- Constipation
- Cough
- Dry skin
- Dyspepsia
- Gamma-glutamyltransferase increased
- Gastritis
- Headache
- Hepatotoxicity
- Hypertension
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