← SynDRA

ATOVAQUONE

SynDRA canonical compound SYN0007078 — structure-anchored drug synonym record

All known targets

• ABCG2
• DHODH
• Dhodh
• MT-CYB
• Malaria DHOdehase
• dhod

Mechanisms of action (all sources)

• mitochondrial electron transport inhibitor
• Inhibitor
• MT-CYB INHIBITOR

Drug classes

• Antimalarial
• Antiprotozoal
• Anti-Infective Agents
• Antimalarials
• Antiparasitic Agents
• Antiprotozoal Agents
• Enzyme Inhibitors

ATC classes

• P01A · AGENTS AGAINST AMOEBIASIS AND OTHER PROTOZOAL DISEASES
• ANTIMALARIALS

Cross-references

• PubChem CID: 74989
• ChEMBL: CHEMBL1450
• DrugBank: DB01117
• ChEBI: CHEBI:575568
• KEGG: D00236
• PDB: AOQ
• Wikipedia: Atovaquone
• TTD: D06ZEE

Synonyms

• 566C80
• mepron
• Atovacuona
• 566C
• NSC-759582
• Atovaquone component of malarone
• Atovaquone component of malarone pediatric
• Mepron
• Wellvone
• Acuvel
• Atavaquone
• Pron
• Atovaquone GlaxoSmithKline brand
• Glaxo Wellcome brand of atovaquone
• GlaxoSmithKline brand of atovaquone
• Malarone Pediatric
• BW 566C
• BW 566C80
• Hydroxynaphthoquinone 566C80
• Atovaquone & Interleukin 12
• BW 556C-80
• BW 566C-80
• BW-A 566C
• DRG-0084
• Hydroxynaphthoquinone, 566C80
• Mepron (TN)
• Mepron (antipneumocystic)
• ATO & IL-12
• Atovaquone (USP/INN)
• Atovaquone [USAN:BAN:INN]
• CRL-8131 & Atovaquone
• 2-(4-(4'-chlorophenyl)cyclohexyl)-3-hydroxy-1,4-naphthoquinone
• 2-(4-(4-Chlorophenyl)cyclohexyl)-3-hydroxy-1,4-naphthoquinone
• 2-(trans-4-(4-chlorophenyl)cyclohexyl)-3-hydroxy-1,4-naphthoquinone
• 2-(trans-4-(p-Chlorophenyl)cyclohexyl)-3-hydroxy-1,4-naphthoquinone
• 2-[trans-4-(4-chlorophenyl)cyclohexyl]-3-hydroxy-1,4-naphthoquinone
• 2-[trans-4-(4-chlorophenyl)cyclohexyl]-3-hydroxynaphthalene-1,4-dione
• 2-[trans-4-(p-Chlorophenyl)cyclohexyl]-3-hydroxy-1,4-naphthoquinone

Reported adverse events

• Insomnia
• Nausea
• Vomiting
• Stevens-Johnson syndrome
• Headache
• Hepatotoxicity
• Cough
• Erythema
• Erythema multiforme
• Hepatitis
• Hypersensitivity
• Pancreatitis