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RIFABUTIN
SynDRA canonical compound SYN0007594 — structure-anchored drug synonym record
| Clinical phase | Launched |
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| Approval status | Approved · Rx/OTC |
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| Primary target(s) | CYP3A4 |
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| Mechanism of action | protein synthesis inhibitor |
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| Indication | human immunodeficiency virus (HIV-1) |
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| Disease area | infectious disease |
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All known targets
- CYP3A4
- rpoA
- rpoB
- rpoC
- rpoZ
Mechanisms of action (all sources)
- protein synthesis inhibitor
- rpoA INHIBITOR
- rpoZ INHIBITOR
- rpoC INHIBITOR
- rpoB INHIBITOR
Drug classes
- Rifamycin Antimycobacterial
- Anti-Bacterial Agents
- Anti-Infective Agents
- Antibiotics, Antitubercular
- Antitubercular Agents
ATC classes
- J04A · DRUGS FOR TREATMENT OF TUBERCULOSIS
- DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD)
Cross-references
Synonyms
- ansamycin
- mycobutin
- rifabutine
- Rifabutine
- Rifabutina
- Ansamycin
- LM-427
- Mycobutin
- Rifabutin component of talicia
- Alfacid
- Ansatipin
- Ansatipine
- Assatipin
- RBT
- Rifabutinum
- Grunenthal Brand of Rifabutin
- Kenfarma Brand of Rifabutin
- Pfizer Brand of Rifabutin
- Rifabutin Pfizer Brand
- Rifabutina [Spanish]
- Rifabutine [French]
- Rifabutinum [Latin]
- Antibiotic LM 427
- LM427
- DRG-0085
- Mycobutin (TN)
- Rifabutin [USAN:BAN:INN]
- Rifabutin (JAN/USP/INN)
- Mycobutin, Ansamycin, LM 427, Ansatipine, Rifabutin
- (9S,12E,14S,15R,16S,17R,18R,19R,20S,21S,22E,24Z)-6,18,20-trihydroxy-1'-isobutyl-14-methoxy-7,9,15,17,19,21,25-heptamethyl-5,10,26-trioxo-3,5,9,10-tetrahydrospiro[9,4-(epoxypentadeca[1,11,13]trienoimino)furo[2',3':7,8]naphtho[1,2-d]imidazole-2,4'-piperidin
- Spiro[9,4-(epoxypentadeca[1,11,13]trienimino)-2H-furo[2',3':7,8]naphth[1,2-d]imidazole-2,4'-piperidine]-5,10,26(3H,9H)-trione, 16-(acetyloxy)-6,18,20-trihydroxy-14-methoxy-7,9,15,17,19,21,25-heptameth
- 1,4-Dihydro-1-deoxy-1',4-didehydro-5'-(2-methylpropyl)-1-oxorifamycin XIV
- 4-Deoxo-3,4-(2-spiro(N-isobutyl-4-piperidyl)-2,5-dihydro-1H-imidazo)-rifamycin S
- 4-N-isobutylspiropiperidylrifamycin S
- 1,4-Dihydro-1-deoxy-1',4-didehydro-5'-(2-methylpropyl)-1-oxorifamycin xiv
- 4-N-Isobutylspiropiperidylrifamycin S
- Ansamicin
- Mycobutin (tn)
Reported adverse events
- Dyspepsia
- Flatulence
- Headache
- Nausea
- Rash
- Uveitis
- Vomiting
- Abdominal pain
- Asthenia
- Corneal deposits
- Eosinophilia
- Eructation
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