← SynDRA

LOSARTAN

SynDRA canonical compound SYN0007815 — structure-anchored drug synonym record

All known targets

• AGTR1
• ABCB1
• GP6
• PDE4D
• PDE4C
• PDE4B
• PDE4A
• PDE3B
• PDE3A
• CYP2C9
• ABCG2
• Agtr2

Mechanisms of action (all sources)

• Angiotensin receptor antagonist
• AGTR1 ANTAGONIST
• Type-1 angiotensin II receptor antagonist

Drug classes

• Angiotensin 2 Receptor Antagonists
• Angiotensin 2 Receptor Blocker
• Angiotensin II Type 1 Receptor Blockers
• Angiotensin Receptor Antagonists
• Anti-Arrhythmia Agents
• Antihypertensive Agents
• Cardiovascular Agents

ATC classes

• C09C · ANGIOTENSIN II RECEPTOR BLOCKERS (ARBs), PLAIN
• ANGIOTENSIN II RECEPTOR BLOCKERS (ARBs), COMBINATIONS

Cross-references

• PubChem CID: 3961
• ChEMBL: CHEMBL191
• DrugBank: DB00678
• ChEBI: CHEBI:6541
• KEGG: D00357
• RxNorm: 52175
• PDB: LSN
• Wikipedia: Losartan
• TTD: D0D1FT
• LINCS BRD: BRD-K76205745

Synonyms

• allisartan
• lortaan
• losartan potassium
• losartan monopotassium
• losartan monopotassium salt
• Allisartan
• Angizaar
• Dup-89
• Exp-3174
• Losartan carboxylic acid
• Losartic
• Lozap
• E-3174
• EXP3174
• HGP-1405
• HGP1405
• NSC-758699
• EXP 3174
• UNII-GD76OCH73X
• CHEBI:74125
• CHEMBL907
• GD76OCH73X
• L-158641
• 2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylic acid
• 2-Butyl-4-chloro-1-[(2'-(1-H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl)methyl]-1-H-imidazole-5-carboxylic acid
• 1H-Imidazole-5-carboxylicacid, 2-butyl-4-chloro-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-
• Carboxylic Acid Metabolite (E-3174)
• Cozaar
• Cozaar (TN)
• DUP 89
• DuP-753
• Hyzaar
• JMS50MPO89
• LOSARTAN POTASSIUM
• Lortaan
• Losartan (INN)
• C22H23ClN6O
• CHEBI:6541

Reported adverse events

• Cough
• Angioedema
• Hepatitis
• Hypotension
• Vasculitis
• Hypersensitivity
• Dysgeusia
• Rhabdomyolysis
• Thrombocytopenia
• Anaphylactic reaction
• Malaise
• Abdominal pain