← SynDRA

TICAGRELOR

SynDRA canonical compound SYN0007868 — structure-anchored drug synonym record

All known targets

• P2RY12
• CYP3A5
• P2ry12
• SLC29A1

Mechanisms of action (all sources)

• P2RY12 NEGATIVE ALLOSTERIC MODULATOR
• Purinergic receptor P2Y12 negative allosteric modulator
• purinergic receptor antagonist
• P2RY12 ANTAGONIST

Drug classes

• Hematologic Agents
• Neurotransmitter Agents
• Platelet Aggregation Inhibitors
• Purinergic Antagonists
• Purinergic P2 Receptor Antagonists
• Purinergic P2Y Receptor Antagonists
• Cytochrome P450 3A4 Inhibitors
• P2Y12 Platelet Inhibitor
• P2Y12 Receptor Antagonists
• P-Glycoprotein Inhibitors
• Cytochrome P450 3A5 Inhibitors
• Phenylalanine Hydroxylase Activators

ATC classes

• B01A · ANTITHROMBOTIC AGENTS

Cross-references

• PubChem CID: 9871419
• ChEMBL: CHEMBL398435
• DrugBank: DB08816
• ChEBI: CHEBI:68558
• KEGG: D09017
• RxNorm: 1116632
• PDB: TIQ
• Wikipedia: Ticagrelor
• TTD: D0WF7L

Synonyms

• brilinta
• AZD 6140
• possia
• brilique
• Possia
• AR-C126532XX
• AZD-6140
• AZD6140
• Brilinta
• Brilique
• UNII-GLH0314RVC
• [14C]-Ticagrelor
• GLH0314RVC
• CHEBI:68558
• (1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-DIFLUOROPHENYL)CYCLOPROPYL]AMINO]-5-(PROPYLTHIO)-3H-1,2,3-TRIAZOLO[4,5-D]PYRIMIDIN-3-YL]-5-(2-HYDROXYETHOXY)-1,2-CYCLOPENTANEDIOL
• (1S,2S,3R,5S)-3-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
• AR-C126532
• Ticagrelor (USAN/INN)
• Brilinta/Brilique
• ticagrelor (ep monograph)
• ticagrelor (usp-rs)
• ticagrelorum
• RefChem:56923
• B01AC24
• DTXCID501436166
• TICARGRELOR
• MFCD09954148
• C23H28F2N6O4S
• Ticagrelor Form
• Ticagrelor [USAN]
• Tigacrelor
• Triafluocyl
• Ticagrelor [USAN:INN:BAN]
• Ticagrelor CRS
• Brilinta (TN)
• Ticagrelor (Standard)
• TICAGRELOR [MI]
• TICAGRELOR [INN]

Reported adverse events

• Hypersensitivity
• Rash
• Bradycardia
• Cheyne-Stokes respiration
• Dizziness
• Gout
• Nausea