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AZACITIDINE

SynDRA canonical compound SYN0007897 — structure-anchored drug synonym record

All known targets

• DNMT1
• DNMT3A

Mechanisms of action (all sources)

• DNMT inhibitor
• DNMT3A INHIBITOR
• DNA (cytosine-5)-methyltransferase 3A inhibitor
• DNMT1 INHIBITOR
• DNA (cytosine-5)-methyltransferase 1 inhibitor

Drug classes

• Nucleic Acid Synthesis Inhibitors
• Nucleoside Metabolic Inhibitor
• Antimetabolites
• Antimetabolites, Antineoplastic
• Antineoplastic Agents
• Enzyme Inhibitors
• Noxae

ATC classes

• L01B · ANTIMETABOLITES

Cross-references

• PubChem CID: 9444
• ChEMBL: CHEMBL1489
• DrugBank: DB00928
• ChEBI: CHEBI:2038
• KEGG: D03021
• RxNorm: 1251
• PDB: 5AE
• Wikipedia: Azacitidine
• TTD: D09FAZ
• LINCS BRD: BRD-K03406345

Synonyms

• 5-azacytidine
• azacytidine
• ladakamycin
• ledakamycin
• vidaza
• U-18496
• Azacitidina
• 5-azacitidine
• Ladakamycin
• NSC-102816
• U-18,496
• Azacitidine accord
• Azacitidine betapharm
• Azacitidine celgene
• Azacitidine kabi
• Azacitidine mylan
• Onureg
• Vidaza
• Azacitidinum
• Azacytidine
• Mylosar
• Mylo sar
• Pharmion Brand of Azacitidine;A 2385
• Antibiotic U 18496
• WR-183027
• Azacitidina [INN-Spanish]
• Azacitidine [USAN:INN]
• Azacitidinum [INN-Latin]
• NS-17
• Pyrimidine antimetabolite: inhibits nucleic acid replication
• Vidaz (TN)
• Vidaza (TN)
• Azacitidine (JAN/USAN/INN)
• S-Triazin-2(1H)-one, 4-amino-1-beta-D-ribofuranosyl-(8CI)
• 2-(beta-D-Ribofuranosyl)-4-amino-1,3,5-triazin-2-one
• 4-Amino-1-(beta-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one
• 4-Amino-1-beta-D-ribofuranosyl-1,3,5-traizin-2(1H)-one
• 4-Amino-1-beta-D-ribofuranosyl-1,3,5-triazine-2(1H)-one

Reported adverse events

• Infection
• Arthralgia
• Nausea
• Neutropenia
• Pneumonia
• Anxiety
• Constipation
• Dizziness
• Fatigue
• Vomiting
• Ecchymosis
• Erythema