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DROSPIRENONE
SynDRA canonical compound SYN0008337 — structure-anchored drug synonym record
| Clinical phase | Launched |
| Approval status | Approved · Rx/OTC |
| Primary target(s) | PGR |
| Mechanism of action | Mineralocorticoid receptor antagonist |
| Indication | contraceptive |
| Disease area | endocrinology |
All known targets
Mechanisms of action (all sources)
- Mineralocorticoid receptor antagonist
- NR3C2 ANTAGONIST
- PGR AGONIST
- NR3C2 BINDER
Drug classes
- Diuretics
- Hormone Antagonists
- Mineralocorticoid Receptor Antagonists
- Natriuretic Agents
- Progestin
ATC classes
- G03A · HORMONAL CONTRACEPTIVES FOR SYSTEMIC USE
- PROGESTOGENS AND ESTROGENS IN COMBINATION
Cross-references
Synonyms
- dihydrospirorenone
- drospirenona
- Drospirenona
- NSC-760103
- ZK-30595
- Drospirenone component of angeliq
- Drospirenone component of beyaz
- Drospirenone component of nextstellis
- Drospirenone component of safyral
- Drospirenone component of yasmin
- Drospirenone component of yaz
- Slynd
- DRSP
- Dehydrospirorenone
- Dihydrospirorenone
- Drospirenonum
- Drospirenone [INN]
- ZK30595
- Angeliq, Drospirenone
- Drospirenona [INN-Spanish]
- Drospirenonum [INN-Latin]
- SH-470
- Drospirenone (JAN/USAN/INN)
- (6R,7R,8R,9S,10R,13S,14S,15S,16S,17S)-1,3',4',6,6a,7,8,9,10,11,12,13,14,15,15a,16-Hexadecahydro-10,13-dimethylspiro-(17H-dicyclopropa(6,7:15,16)cyclopenta(a)phenanthrene-17,2'(5'H)-furan)-3,5'(2H)-dione
- 1,2-Dihydrospirorenone
- 1,2-dihydro-spirorenone
- 17-Hydroxy-6beta,7beta:15beta,16beta-dimethylene-3-oxo-17alpha-pregn-4-ene-21-carboxylic acid, gamma-lactone
- 3-oxo-6alpha,7alpha,15alpha,16alpha-tetrahydro-7'H,16'H-dicyclopropa[6,7;15,16]-17alpha-pregn-4-ene-21,17-carbolactone
- 6-beta,7-beta;15-beta,16-beta-Dimethylene-3-oxo-17-alpha-pregn-4-ene-21,17-carbolactone
- 6beta,7beta,15beta,16beta-dimethylen-3-oxo-17alpha-pregn-4-en-21,17-carbolacton
- 6beta,7beta,15beta,16beta-dimethylene-3-oxo-17alpha-pregn-4-ene-21,17 carbolactone
- 6beta,7beta;15beta,16beta-Dimethylene-3-oxo-17alpha-pregn-4-ene-21,17-carbolactone
- Spiro(17H-dicyclopropa(6,7:15,16)cyclopenta(a)phenanthrene-17,2'(5'H)-furan)-3,5'(2H)-dione, 1,3',4',6,7,8,9,10,11,12,13,14,15,16,20,21-hexadecahydro-10,13-dimethyl-, (6R-(6alpha,7alpha,8beta,9alpha,10beta,13beta,14alpha,15alpha,16alpha,17beta
- CHEBI:50838
- N295J34A25
- NSC 760103
- (1R,2R,4R,10R,11S,14S,15S,16S,18S,19S)-10,14-dimethylspiro[hexacyclo[9.8.0.0^{2,4}.0^{5,10}.0^{14,19}.0^{16,18}]nonadecane-15,2'-oxolan]-5-ene-5',7-dione
- CAS-67392-87-4
Reported adverse events
- Cancer
- Dementia
- DVT
- Breast cancer
- Cardiovascular disorder
- TIA
- Headache
- Depression
- Hypersensitivity
- Acne
- Nausea
- Chloasma
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