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ESZOPICLONE

SynDRA canonical compound SYN0008487 — structure-anchored drug synonym record

All known targets

• GABRA1
• GABRA3
• GABRA4
• GABRA5
• GABRB2
• GABRA2
• GABRG3
• GABRG2
• GABRG1
• GABRQ
• GABRP
• GABRB3

Mechanisms of action (all sources)

• GABA receptor agonist
• TSPO AGONIST
• GABRA2 POSITIVE ALLOSTERIC MODULATOR
• GABRA4 POSITIVE ALLOSTERIC MODULATOR
• GABRA1 POSITIVE ALLOSTERIC MODULATOR
• GABRG2 POSITIVE ALLOSTERIC MODULATOR
• GABRB2 POSITIVE ALLOSTERIC MODULATOR
• GABRG3 POSITIVE ALLOSTERIC MODULATOR
• GABRA3 POSITIVE ALLOSTERIC MODULATOR
• GABRA5 POSITIVE ALLOSTERIC MODULATOR

Drug classes

• Central Nervous System Agents
• Central Nervous System Depressants
• Hypnotics and Sedatives

ATC classes

• N05C · HYPNOTICS AND SEDATIVES

Cross-references

• PubChem CID: 887
• ChEMBL: CHEMBL1522
• DrugBank: DB00402
• ChEBI: CHEBI:53760
• KEGG: D02624
• RxNorm: 461016
• Wikipedia: Eszopiclone
• TTD: D06ZII
• LINCS BRD: BRD-K29220403

Synonyms

• esopiclone
• lunesta
• Eszopiclona
• Zopiclone s-form
• Estorra
• Eszopiclon
• (S)-ZOPICLONE
• GSK-1755165
• Lunesta
• Eszopiclone civ
• Esopiclone
• Lunivia
• Estorra (TN)
• Eszopiclone [USAN:INN]
• KS-1055
• SEP-0227018
• SEP-0227108
• SEP-190
• SEP-225441
• Eszopiclone (JAN/USAN/INN)
• [(7S)-6-(5-chloropyridin-2-yl)-5-oxo-7H-pyrrolo[3,4-b]pyrazin-7-yl] 4-methylpiperazine-1-carboxylate
• (+)-(5S)-6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo(3,4-b)pyrazin-5-yl 4-methylpiperazine-1-carboxylate
• (5S)-6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo(3,4-b)pyrazin-5-yl 4-methylpiperazine-1-carboxylate
• (5S)-6-(5-chloropyridin-2-yl)-7-oxo-5H,6H,7H-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate
• (5S)-6-(5-chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate
• (S)-Zopiclone
• (plus)-Zopiclone
• 1-Piperazinecarboxylic acid, 4-methyl-, (5S)-6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo(3,4-b)pyrazin-5-yl ester
• eszopiclone civ (usp-rs)
• UZX80K71OE
• Zopiclone s-
• eszopiclone (usp monograph)
• (+)-Zopiclone
• eszopiclona
• CHEBI:53760
• DTXCID6026086
• eszopiclonum
• RefChem:56355

Reported adverse events

• Anxiety
• Depression
• Dizziness
• Dyspepsia
• Hallucination
• Headache
• Nausea
• Nervousness
• Pruritus
• Rash
• Somnolence
• Vomiting