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TENOFOVIR DISOPROXIL
SynDRA canonical compound SYN0009002 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | CYP1A2 | CYP3A4 |
|---|
| Mechanism of action | nucleoside reverse transcriptase inhibitor |
|---|
| Indication | hepatitis B | human immunodeficiency virus (HIV-1) |
|---|
| Disease area | infectious disease |
|---|
All known targets
- CYP1A2
- CYP3A4
- HIV RT
- gag-pol
- pol
Mechanisms of action (all sources)
- nucleoside reverse transcriptase inhibitor
- Modulator
- pol INHIBITOR
Drug classes
- Anti-HIV Agents
- Anti-Infective Agents
- Anti-Retroviral Agents
- Antiviral Agents
- Enzyme Inhibitors
- Nucleic Acid Synthesis Inhibitors
- Reverse Transcriptase Inhibitors
ATC classes
- J05A · DIRECT ACTING ANTIVIRALS
Cross-references
Synonyms
- viread
- tenofovir disoproxil fumarate
- Tenofovir bis(isopropyloxycarbonyloxymethyl) ester
- (r)-bis(poc)pmpa
- Bis-poc-pmpa
- GS-4331
- Tenofovir disoproxil component of stribild
- Viread
- Bis(POC)PMPA
- bis-POC-PMPA
- tenofovir bis(isopropyloxycarbonyloxymethyl) ester
- F4YU4LON7I
- CHEBI:63717
- STRIBILD COMPONENT TENOFOVIR DISOPROXIL
- RefChem:187852
- DTXCID2031249
- C19H30N5O10P
- MFCD00952920
- UNII-F4YU4LON7I
- Tenofovir disoproxil Impurity 1
- SCHEMBL52793
- MLS006010919
- orb1300062
- SCHEMBL29376425
- BDBM77145
- Bis(POC)-PMPA;GS 4331
- JFVZFKDSXNQEJW-CQSZACIVSA-N
- Bis(isopropyloxymethylcarbonyl)PMPA
- ALBB-038604
- EBC-27267
- HY-13782A
- MSK160697
- s5959
- TENOFOVIR DISOPROXIL [WHO-DD]
- AKOS015895093
- Viread(TM) (*1:1 Fumarate salt*)
- CS-5922
Reported adverse events
- Lactic acidosis
- Lactic acid
- Fanconi syndrome
- Rash
- Dizziness
- Headache
- Hepatomegaly
- Nausea
- Insomnia
- Arthralgia
- Vomiting
- Depression
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