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AZATHIOPRINE
SynDRA canonical compound SYN0009026 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | PPAT |
|---|
| Mechanism of action | Dehydrogenase inhibitor |
|---|
| Indication | renal homotransplantation | rheumatoid arthritis |
|---|
| Disease area | rheumatology | transplant |
|---|
All known targets
- PPAT
- ABCC4
- ABCC5
- ABCG2
- HPRT1
- IMPDH1
- RAC1
- TPMT
Mechanisms of action (all sources)
- Dehydrogenase inhibitor
- PPAT INHIBITOR
- Amidophosphoribosyltransferase inhibitor
Drug classes
- Nucleic Acid Synthesis Inhibitors
- Antimetabolites
- Antimetabolites, Antineoplastic
- Antineoplastic Agents
- Antirheumatic Agents
- Immunologic Factors
- Immunosuppressive Agents
- Noxae
- Purine Antimetabolite
ATC classes
- L04A · IMMUNOSUPPRESSANTS
Cross-references
Synonyms
- BW 57-322
- azathioprine sulfate
- azamune
- azanin
- azathioprin
- azathropine
- azothioprine
- azathioprine sodium
- Azatioprina
- Azathioprinum
- BW-57-322
- NSC-39084
- Azamune
- Azapress
- Azasan
- Berkaprine
- Immunoprin 50
- Imuran
- Jayempi
- Kentaprine
- Oprisine 50
- Azamun
- Azanin
- Azathioprin
- Azathiopurine
- Azatioprin
- Azothioprine
- Ccucol
- Cytostatics
- Immuran
- Imurek
- Imurel
- Methylnitroimidazolylmercaptopurine
- Muran
- Azamun [Czech]
- Azathioprine sodium
- Azatiopr in
- A 4638
Reported adverse events
- P
- T-cell lymphoma
- Infection
- Nausea
- Hepatotoxicity
- Leukopenia
- Lymphoma
- Vomiting
- Death
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