← SynDRA

DANUSERTIB

SynDRA canonical compound SYN0009120 — structure-anchored drug synonym record

All known targets

• AURKA
• AURKB
• AURKC
• FGFR1
• NTRK1
• RET
• BCR
• SLK

Mechanisms of action (all sources)

• aurora kinase inhibitor
• Growth factor receptor inhibitor
• AURKB INHIBITOR
• Serine/threonine-protein kinase Aurora inhibitor
• AURKC INHIBITOR
• AURKA INHIBITOR

Cross-references

• PubChem CID: 11442891
• ChEMBL: CHEMBL402548
• DrugBank: DB11778
• ChEBI: 94490
• PDB: 627
• TTD: D02RJY
• LINCS BRD: BRD-K07881437

Synonyms

• PHA-739358
• DANUSERTIB (PHA-739358)
• PHA 739358
• Danusertib, PHA-739358
• (R)-N-(5-(2-methoxy-2-phenylacetyl)-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl)-4-(4-methylpiperazin-1-yl)benzamide
• 5-Amido-pyrrolopyrazole 9d
• Danusertib (PHA-739358)
• Danusertib [INN]
• PHA739358
• CHEMBL402548
• M3X659D0FY
• PHA-739358 (danusertib)
• MMV676600
• N-(5-((2R)-2-methoxy-2-phenylacetyl)-1,4,5,6-tetrahydropyrrolo(3,4-c)pyrazol-3-yl)-4-(4-methylpiperazin-1-yl)benzamide
• N-[5-((2R)-2-Methoxy-2-phenylethanoyl)-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl]-4-(4-methylpiperazin-1-yl)benzamide
• UNII-M3X659D0FY
• (R)-N-(5-(2-Methoxy-2-phenylacetyl)-1,4,5,6-tetrahydropyrrolo-[3,4-c]pyrazol-3-yl)-4-(4-methylpiperazin-1-yl)benzamide
• N-[5-[(2R)-2-methoxy-2-phenylacetyl]-4,6-dihydro-1H-pyrrolo[3,4-c]pyrazol-3-yl]-4-(4-methylpiperazin-1-yl)benzamide
• N-{5-[(2R)-2-methoxy-2-phenylethanoyl]-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl}-4-(4-methylpiperazin-1-yl)benzamide
• DANUSERTIB [WHO-DD]
• PHA-739358,Danusertib
• MLS006011243
• Danusertib; PHA-739358
• SCHEMBL466509
• GTPL7937
• Danusertib - PHA-739358
• BDBM12985
• CHEBI:94490
• 2j50
• BCPP000266
• DTXSID301002864
• BCP01750
• EX-A1599
• ZINC6718723
• MFCD12024692
• NSC784415
• NSC800086
• AKOS015896691