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MARAVIROC
SynDRA canonical compound SYN0009157 — structure-anchored drug synonym record
| Clinical phase | Launched |
| Approval status | Approved · Rx/OTC |
| Primary target(s) | CCR5 | CYP3A5 |
| Mechanism of action | CC chemokine receptor antagonist |
| Indication | human immunodeficiency virus (HIV-1) |
| Disease area | infectious disease |
All known targets
Mechanisms of action (all sources)
- CCR5 ANTAGONIST
- C-C chemokine receptor type 5 antagonist
- CC chemokine receptor antagonist
Drug classes
- Chemokine Co-receptor 5 Antagonists
- CCR5 Co-receptor Antagonist
- Anti-HIV Agents
- Anti-Infective Agents
- Anti-Retroviral Agents
- Antiviral Agents
- CCR5 Receptor Antagonists
- HIV Fusion Inhibitors
ATC classes
- J05A · DIRECT ACTING ANTIVIRALS
Cross-references
Synonyms
- MD6P741W8A
- UK-427857
- maravirok
- marawirok
- celsentri
- selzentry
- Rel-maraviroc
- Uk-427,857
- Celsentri
- Selzentry
- UK 427857
- UK-427,857
- UNII-MD6P741W8A
- CHEMBL256907
- MVC
- CHEMBL1201187
- CHEBI:63608
- 4,4-difluoro-N-[(1S)-3-[(1R,5S)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[321]octan-8-yl]-1-phenylpropyl]cyclohexane-1-carboxamide
- Isopropyl, 4,4-difluoro-N-((1S)-3-{(1R,3s,5S)-3-(3-methyl-5-(propan-2-yl)-4H-1,2,4-triazol-4-yl)-8-azabicyclo(321)octan-8-yl}-1-phenylpropyl)cyclohexanecarboxamide
- Maraviroc [USAN]
- Celsentri (TN)
- Celsentri(TM)
- PRO 140 & Maraviroc
- Selzentry (TN)
- Selzentry(TM)
- UK-427,857 maraviroc (MVC)
- Exo-4,4-Difluoro-N-[3-[3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[321]oct-8-yl]-1(S)-phenylpropyl]cyclohexanecarboxamide
- PRO 140 (Anti-CCR5 monoclonal antibody) & exo-4,4-Difluoro-N-[3-[3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[321]oct-8-yl]-1(S)-phenylpropyl]cyclohexanecarboxamide
- 4,4-Difluoro-N-((1S)-3-(exo-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo(321)oct-8-yl)-1-phenylpropyl)cyclohexanecarboxamide
- [3H]maraviroc
- SELZENTRY
Reported adverse events
- Hepatotoxicity
- Rash
- Myositis
- Stevens-Johnson syndrome
- Infection
- Acne
- Alopecia
- Anxiety
- Bronchitis
- Conjunctivitis
- Constipation
- Cough
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