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ATROPINE
SynDRA canonical compound SYN0010764 — structure-anchored drug synonym record
| Clinical phase | Launched |
| Approval status | Approved · Rx/OTC |
| Primary target(s) | CHRM5 |
| Mechanism of action | Acetylcholine receptor antagonist |
| Indication | amblyopia | cycloplegia | mydriasis |
| Disease area | ophthalmology |
All known targets
- CHRM1
- CHRM2
- CHRM3
- CHRM5
- CHRM4
- ADRA1D
- Chrm5
- SLC22A1
- HTR2C
- HTR2A
- HRH1
- GPM3
Mechanisms of action (all sources)
- Acetylcholine receptor antagonist
- CHRM3 ANTAGONIST
- Muscarinic acetylcholine receptor M3 antagonist
- CHRM1 ANTAGONIST
- Muscarinic acetylcholine receptor M1 antagonist
- CHRM2 ANTAGONIST
- Muscarinic acetylcholine receptor M2 antagonist
- CHRM5 ANTAGONIST
Drug classes
- Cholinergic Muscarinic Antagonists
- Cholinergic Antagonists
- Anticholinergic
- Adjuvants, Anesthesia
- Anti-Arrhythmia Agents
- Anti-Asthmatic Agents
- Bronchodilator Agents
- Cardiovascular Agents
- Central Nervous System Agents
- Cholinergic Agents
- Muscarinic Antagonists
- Mydriatics
ATC classes
- A03B · BELLADONNA AND DERIVATIVES, PLAIN
- S01F · MYDRIATICS AND CYCLOPLEGICS
- ANTISPASMODICS IN COMBINATION WITH PSYCHOLEPTICS
Cross-references
Synonyms
- (+/-)-Atropine
- atropin
- atropinum sulphuricum
- DL-Hyoscyamine
- tropine tropate
- atropine sulfate
- Atropinum
- Dl-hyoscyamine
- Atroject
- Atropen
- Atrophate
- Atropine (autoinjector)
- Atropine component of atnaa
- Atropine component of duodote
- dl-Hyoscyamine
- Atropin
- dl-Tropyltropate
- Atropinol
- Atropina
- Eyesules
- Troyl tropate
- Isopto Atropine
- Atropin [German]
- Atropina [Italian]
- Atropin-flexiolen
- (+,-)-Tropyl tropate
- DL-Tropyl tropate
- Tropine, tropate (ester)
- Tropic acid, ester with tropine
- Atropine sulfate
- CCRIS 3080
- Atropine (USP)
- Tropic acid, 3-alpha-tropanyl ester
- Atropt
- HSDB 2199
- DL-Tropanyl
- Anaspaz
- Atropair
Reported adverse events
- Dehydration
- Hypersensitivity
- Photophobia
- Eye pain
- Constipation
- Anhidrosis
- Stevens-Johnson syndrome
- Glaucoma
- Coma
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