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IVABRADINE

SynDRA canonical compound SYN0011502 — structure-anchored drug synonym record

All known targets

• HCN4
• HCN1
• HCN2
• HCN3
• Hcn1
• Hcn2

Mechanisms of action (all sources)

• HCN4 BLOCKER
• Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 blocker
• HCN channel blocker
• potassium channel blocker
• sodium channel blocker
• hcn channel blocker, potassium channel blocker, sodium channel blocker
• HCN1 BLOCKER
• HCN2 BLOCKER
• HCN3 BLOCKER

Drug classes

• Cardiovascular Agents
• Hyperpolarization-activated Cyclic Nucleotide-gated Channel Blocker
• Hyperpolarization-activated Cyclic Nucleotide-gated Channel Antagonists

ATC classes

• C01E · OTHER CARDIAC PREPARATIONS
• BETA BLOCKING AGENTS, OTHER COMBINATIONS

Cross-references

• PubChem CID: 132999
• ChEMBL: CHEMBL471737
• DrugBank: DB09083
• ChEBI: CHEBI:85969
• KEGG: D07165
• RxNorm: 1649480
• PDB: VNZ
• Wikipedia: Ivabradine
• TTD: D0S9QA

Synonyms

• corlanor
• corlentor
• ivabradine hydrochloride
• coraxan
• procoralan
• ivabradine HCl
• Ivabradina
• S 16257
• Procoralan
• Corlanor
• Corlentor
• UNII-3H48L0LPZQ
• S-16257
• S 16257-2
• 3H48L0LPZQ
• CHEMBL471737
• CHEBI:85966
• C27H36N2O5
• 7,8-Dimethoxy-3-(3-(((4,5-dimethoxybenzocyclobutan-1-yl)methyl)methylamino)propyl)-1,3,4,5-tetrahydro-2H-benzazepin-2-one
• S-16260-2
• s16257
• (S)-3-(3-(((3,4-Dimethoxybicyclo(4.2.0)octa-1,3,5-trien-7-yl)methyl)methylamino)propyl)-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one
• Ivabradine [INN]
• Ivabradinum
• RefChem:56735
• S162572
• S162602
• S 162572
• S 162602
• S-16257-2
• DTXCID3028215
• C01EB17
• Ivabradine [USAN:INN:BAN]
• ACRHBAYQBXXRTO-OAQYLSRUSA-N
• VNZ
• IVABRADINE [MI]
• Ivabradine (USAN/INN)
• IVABRADINE [USAN]

Reported adverse events

• Atrial fibrillation
• Hypertension