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SIMEPREVIR
SynDRA canonical compound SYN0011604 — structure-anchored drug synonym record
| Clinical phase | Launched |
| Approval status | Approved · OTC |
| Primary target(s) | CYP1A2 | CYP2C19 | CYP2C8 | CYP3A4 | SLCO1B3 |
| Mechanism of action | HCV inhibitor |
| Indication | hepatitis C |
| Disease area | infectious disease |
All known targets
- CTSS
- CYP1A2
- CYP2C19
- CYP2C8
- CYP3A4
- HCV NS3/4A
- NS3
- NS4A
- SLCO1B3
Mechanisms of action (all sources)
- HCV inhibitor
- Modulator
- NS3 INHIBITOR
- NS4A INHIBITOR
Drug classes
- Anti-Infective Agents
- Antiviral Agents
- Enzyme Inhibitors
- Protease Inhibitors
- Cytochrome P450 1A2 Inhibitors
- Cytochrome P450 3A4 Inhibitors
- HCV NS3/4A Protease Inhibitors
- Hepatitis C Virus NS3/4A Protease Inhibitor
- P-Glycoprotein Inhibitors
- Organic Anion Transporting Polypeptide 1B1 Inhibitors
- Organic Anion Transporting Polypeptide 1B3 Inhibitors
- Breast Cancer Resistance Protein Inhibitors
ATC classes
- J05A · DIRECT ACTING ANTIVIRALS
Cross-references
Synonyms
- olysio
- TMC-435
- TMC435350
- simeprevir sodium
- Tmc435
- TMC-435350
- TMC436
- TMC 435
- TMC435
- 9WS5RD66HZ
- simeprevirum
- RefChem:183072
- J05AP05
- DTXCID001510258
- HSDB 8227
- Olysio
- Simeprevir [USAN]
- C38H47N5O7S2
- SIMEPREVIR SODIUM [JAN]
- MFCD25563225
- HCV-PI
- SIMEPREVIR [MI]
- SIMEPREVIR [INN]
- SIMEPREVIR [JAN]
- SIMEPREVIR [VANDF]
- SIMEPREVIR [WHO-DD]
- SCHEMBL826061
- GTPL7367
- orb1302653
- SCHEMBL31016950
- CHEBI:134743
- BDBM50336504
- s5015
- AKOS025401966
- CCG-270435
- FS65167
- AC-27651
- AS-56205
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