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FLUDARABINE
SynDRA canonical compound SYN0011622 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | RRM1 |
|---|
| Mechanism of action | DNA synthesis inhibitor |
|---|
| Indication | chronic lymphocytic leukemia (CLL) |
|---|
| Disease area | hematologic malignancy |
|---|
All known targets
Mechanisms of action (all sources)
- DNA synthesis inhibitor
- ribonucleotide reductase inhibitor
- ADA INHIBITOR
Cross-references
Synonyms
- Fludarabina
- 2-f-araa
- 2-fluoro ara-a
- 2-fluorovidarabine
- Fluradosa
- NSC-118218
- NSC-118218H
- FaraA
- Fludarabinum
- Fludarabina [Spanish]
- Fludarabine [INN]
- Fludarabinum [Latin]
- SQ Fludarabine
- Fludara, Fludarabine
- Fludarabine (INN)
- Fluradosa (TN)
- F-Ara-A
- (2R,3S,4S,5R)-2-(6-amino-2-fluoro-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
- (2R,3S,4S,5R)-2-(6-amino-2-fluoropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
- 2-F-ara-A
- 2-Fluoro Ara-A
- 2-Fluoro-9-beta-D-arabinofuranosyladenine
- 9-beta-D-Arabinofuranosyl-2-fluoroadenine
- 9-beta-D-arabinofuranosyl-2-fluoro-9H-purin-6-amine
- 9H-Purin-6-amine, 9-beta-D-arabinofuranosyl-2-fluoro-(9CI)
- P2K93U8740
- 2-F-ARAA
- fludarabine phosphate impurity e (ep impurity)
- NSC 118218
- CCRIS 3382
- 9H-Purin-6-amine, 9-beta-D-arabinofuranosyl-2-fluoro-
- DTXCID2019657
- 2-Fluoroadenine arabinoside
- NSC118218
- RefChem:58475
- L01BB05
- 2-Fluoro-9-beta-arabinofuranosyladenine
- 9-b-d-arabinofuranosyl-2-fluoroadenine
Reported adverse events
- P
- Evans syndrome
- Erythema multiforme
- Infection
- Myelosuppression
- Neoplasm
- Pneumonia
- Stevens-Johnson syndrome
- Skin toxicity
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