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PALIPERIDONE
SynDRA canonical compound SYN0014173 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | DRD2 | HTR2A | HTR7 |
|---|
| Mechanism of action | dopamine receptor antagonist | serotonin receptor antagonist |
|---|
| Indication | schizophrenia |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- HTR2A
- DRD2
- HTR1A
- HTR7
- HTR1E
- HRH1
- HTR1D
- HTR1B
- ADRA1A
- PTGER3
- KCNH2
- HTR6
Mechanisms of action (all sources)
- DRD2 ANTAGONIST
- Dopamine D2 receptor antagonist
- HTR2A ANTAGONIST
- Serotonin 2a (5-HT2a) receptor antagonist
- dopamine receptor antagonist
- serotonin receptor antagonist
- HTR1A ANTAGONIST
- HTR1D ANTAGONIST
- HTR1E ANTAGONIST
- HRH1 ANTAGONIST
- HTR1B ANTAGONIST
Drug classes
- Atypical Antipsychotic
- Antipsychotic Agents
- Central Nervous System Agents
- Central Nervous System Depressants
- Dopamine Agents
- Dopamine Antagonists
- Dopamine D2 Receptor Antagonists
- Neurotransmitter Agents
- Psychotropic Drugs
- Serotonin 5-HT2 Receptor Antagonists
- Serotonin Agents
- Serotonin Antagonists
ATC classes
Cross-references
Synonyms
- RO76477
- RO 76477
- invega
- xeplion
- Paliperidona
- 9-hydroxyrisperidone
- NSC-759623
- R-76477
- RO-76477
- Invega
- Risperidone impurity, 9-hydroxyrisperidone-
- Xeplion
- Invega Sustenna
- Paliperidone palmitate
- JNS-010
- Paliperidone (depot injection, NanoCrystal)
- Paliperidone (injectable, NanoCrystal), Elan
- Paliperidone (depot injection, NanoCrystal), Johnson & Johnson
- 9-Hydroxyrisperidone
- 9-OH-risperidone
- 3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-9-hydroxy-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one
- C23H27FN4O3
- R 76477
- 3-[2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-9-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one
- 3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
- CHEMBL1621
- 4H-Pyrido(1,2-a)pyrimidin-4-one, 3-(2-(4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl)ethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-
- CHEBI:83804
- 144598-75-4 (free base)
- NSC 759623
- 838F01T721
- (9RS)-3-(2-(4-(6-Fluoro-1,2-benzisoxazol-3-yl)piperidin-1-yl))ethyl)-9-hydroxy-2-methyl-6,7,8,9-tetrahydro-4H-pyrido(1,2-a)pyrimidin-4-one
- 3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-9-hydroxy-2-methyl-4H,6H,7H,8H,9H-pyrido[1,2-a]pyrimidin-4-one
- 4H-Pyrido[1,2-a]pyrimidin-4-one, 3-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-
- Paliperidone [INN]
- PALLIPERIDONE
- 9-hydroxy risperidone
- HSDB 8148
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