← SynDRA

CLEMASTINE

SynDRA canonical compound SYN0014227 — structure-anchored drug synonym record

All known targets

• HRH1
• ADRA1D
• ADRA2A
• SLC6A3
• SLC6A2
• SLC22A1
• SIGMAR1
• Pgrmc1
• KCNH2
• Htr1b
• HTR6
• HTR2C

Mechanisms of action (all sources)

• Histamine receptor antagonist
• HRH1 ANTAGONIST
• Histamine H1 receptor antagonist

Drug classes

• Anti-Allergic Agents
• Antipruritics
• Dermatologic Agents
• Histamine Agents
• Histamine Antagonists
• Histamine H1 Antagonists
• Neurotransmitter Agents

ATC classes

• R06A · ANTIHISTAMINES FOR SYSTEMIC USE
• D04A · ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.

Cross-references

• PubChem CID: 26987
• ChEMBL: CHEMBL1626
• DrugBank: DB00283
• ChEBI: CHEBI:3738
• KEGG: D00666
• RxNorm: 2578
• Wikipedia: Clemastine
• TTD: D0C5XC
• LINCS BRD: BRD-K30240666

Synonyms

• meclastine
• clemastine fumarate
• Clemastina
• Clemastin
• HS-592
• NSC-756685
• Clemastinum
• Meclastin
• Meclastine
• Mecloprodin
• Tavegyl
• Tavist
• CLEMASTINE FUMARATE
• Clemastina [INN-Spanish]
• Clemastine [USAN:BAN]
• Clemastinum [INN-Latin]
• Tavegyl (TN)
• Tavist (TN)
• Tavist (*Fumarate*)
• (+)-(2R)-2-(2-(((R)-p-Chloro-alpha-methyl-alpha-phenylbenzyl)oxy)ethyl)-1-methylpyrrolidine
• (+)-(2R)-2-[2-[[(R)-p-Chloro-alpha-methyl-alpha-phenylbenzyl]oxy]ethyl]-1-methylpyrrolidine
• (2R)-2-(2-{[(1R)-1-(4-chlorophenyl)-1-phenylethyl]oxy}ethyl)-1-methylpyrrolidine
• (2R)-2-[2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]ethyl]-1-methylpyrrolidine
• (2R)-2-{2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]ethyl}-1-methylpyrrolidine
• 2(R)-[2-[(1R)-(4-Chlorophenyl)-1-phenyl-ethoxy]ethyl-1-methylpyrrolidine
• 2-(2-(4-Chlor-alpha-methylbenzhydryloxy)ethyl)-1-methylpyrrolidin
• HS 592
• NSC 756685
• CHEBI:3738
• RefChem:56359
• DTXCID502832
• D04AA14
• R06AA04
• HS592
• C21H26ClNO
• MLS002154260
• CLEMASTINE [USAN]
• NCGC00016710-01

Reported adverse events

• Hypotension
• Sedation