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OLAPARIB

SynDRA canonical compound SYN0014230 — structure-anchored drug synonym record

All known targets

• PARP1
• PARP2
• PARP3
• PARP10
• PARP12
• PARP15
• PARP16
• PARP4
• PARP6
• TNKS
• TNKS2

Mechanisms of action (all sources)

• PARP inhibitor
• PARP1 INHIBITOR
• PARP 1, 2 and 3 inhibitor
• PARP3 INHIBITOR
• PARP2 INHIBITOR

Drug classes

• Antineoplastic Agents
• Enzyme Inhibitors
• Poly(ADP-ribose) Polymerase Inhibitors
• Poly(ADP-Ribose) Polymerase Inhibitors
• Poly(ADP-Ribose) Polymerase Inhibitor

ATC classes

• L01X · OTHER ANTINEOPLASTIC AGENTS

Cross-references

• PubChem CID: 23725625
• ChEMBL: CHEMBL521686
• DrugBank: DB09074
• ChEBI: CHEBI:83766
• KEGG: D09730
• RxNorm: 1597582
• PDB: 09L
• Wikipedia: Olaparib
• TTD: D0J9HW
• LINCS BRD: BRD-K02113016

Synonyms

• lynparza
• AZD2281
• AZ-2281
• AZ2281
• AZD-2281
• KU-0059436
• KU-59436
• KU0059436
• Lynparza
• NSC-747856
• OLAPARIB (AZD2281)
• OLAPARIB COMPONENT OF KEYLYNK-010
• OLAPARIBAZD-2281AZD 2281KU 59436KU-59436LYNPARZAAZD2281KU59436O-9201
• Acylpiperazine analogue, 47
• Olaparib, KU-0059436, AZD2281,KU0059436, AZD2281
• 4-[(3-{[4-Cyclopropylcarbonyl)piperazin-4-yl]carbonyl}-4-fluorophenyl)methyl]phtalazin-1(2H)-one
• 4-[3-(4-Cyclopropanecarbonyl-piperazine-1-carbonyl)-4-fluoro-benzyl]-2H-phthalazin-1-one
• AZD 2281
• KU 0059436
• 1-(Cyclopropylcarbonyl)-4-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]-2-fluorobenzoyl]piperazine
• Olaparib (AZD-2281)
• 4-(3-(4-(Cyclopropanecarbonyl)piperazine-1-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one
• KU 59436
• Olaparib (AZD2281, Ku-0059436)
• 4-[[3-[4-(Cyclopropanecarbonyl)piperazine-1-carbonyl]-4-fluorophenyl]methyl]-2H-phthalazin-1-one
• MFCD13185161
• WOH1JD9AR8
• NSC 747856
• C24H23FN4O3
• CHEBI:83766
• 4-(3-{[4-(Cyclopropylcarbonyl)piperazin-1-Yl]carbonyl}-4-Fluorobenzyl)phthalazin-1(2h)-One
• KEYLYNK-010 COMPONENT OLAPARIB
• KU59436
• Olaparib [INN]
• 4-[(3-{[4-(Cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorophenyl)methyl]phthalazin-1(2H)-one
• OLAPARIB cpd
• Olaparib (AZD2281; Ku-0059436)
• Olaparib [USAN:INN]

Reported adverse events

• Cough
• Dizziness
• Dysgeusia
• Dyspepsia
• Erythema nodosum
• Fatigue
• Headache
• Hypersensitivity
• Leukopenia
• Lymphopenia
• Nausea
• Neutropenia