← SynDRA

N,N-HEXAMETHYLENEAMILORIDE

SynDRA canonical compound SYN0014409 — structure-anchored drug synonym record

All known targets

• GNRHR
• ADRA2A
• ADRA2C
• SLC9A1

Mechanisms of action (all sources)

• Sodium/hydrogen antiport inhibitor
• ADRA2A NEGATIVE ALLOSTERIC MODULATOR
• GNRHR NEGATIVE ALLOSTERIC MODULATOR
• GNRHR MODULATOR (ALLOSTERIC MODULATOR)
• ADRA2C MODULATOR (ALLOSTERIC MODULATOR)

Drug classes

• Antineoplastic Agents

Cross-references

• PubChem CID: 1794
• ChEMBL: CHEMBL501701
• ChEBI: 76400
• PDB: HMX
• TTD: D02YIW
• LINCS BRD: BRD-K40990712

Synonyms

• 5-(N,N-hexamethylene)-amiloride
• 5-(N,N-Hexamethylene)amiloride
• Hexamethyleneamiloride
• Hexamethylene amiloride
• HMA-5
• HMA
• C12H18ClN7O
• 3-Amino-6-chloro-5-(1-homopiperidyl)-N-(diaminomethylene)pyrazinecarboxamide
• CHEBI:76400
• 3-amino-5-(azepan-1-yl)-6-chloro-N-(diaminomethylene)pyrazine-2-carboxamide
• 3-Amino-N-(aminoiminomethyl)-6-chloro-5-(hexahydro-1H-azepin-1-yl)pyrazinecarboxamide
• Pyrazinecarboxamide, 3-amino-N-(aminoiminomethyl)-6-chloro-5-(hexahydro-1H-azepin-1-yl)-
• 5-HMA
• Spectrum_001596
• hexamethyleneamiloride
• RefChem:531434
• DTXCID7084679
• 5-(N,N-hexamethylene)-Amiloride
• Hexamethylene amiloride;HMA
• RQQJJXVETXFINY-UHFFFAOYSA-N
• SpecPlus_000779
• Spectrum2_001669
• Spectrum3_001662
• Spectrum4_000623
• Spectrum5_001388
• Lopac-A-9561
• Lopac0_000104
• BSPBio_003443
• KBioGR_001206
• KBioSS_002076
• MLS002153208
• BIDD:GT0357
• DivK1c_006875
• SPECTRUM1504215
• SPBio_001857
• GTPL1192
• orb2893603
• SCHEMBL7862943
• SCHEMBL9852488