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FOSAMPRENAVIR

SynDRA canonical compound SYN0016568 — structure-anchored drug synonym record

All known targets

• HIV PR
• gag-pol
• pol

Mechanisms of action (all sources)

• protease inhibitor
• Inhibitor
• pol INHIBITOR

Drug classes

• HIV Protease Inhibitors
• Anti-Bacterial Agents
• Anti-HIV Agents
• Anti-Infective Agents
• Anti-Retroviral Agents
• Antibiotics, Antitubercular
• Antitubercular Agents
• Antiviral Agents
• Enzyme Inhibitors
• Protease Inhibitors
• Viral Protease Inhibitors
• Protease Inhibitor

ATC classes

• J05A · DIRECT ACTING ANTIVIRALS

Cross-references

• PubChem CID: 131536
• ChEMBL: CHEMBL1664
• DrugBank: DB01319
• ChEBI: CHEBI:82941
• KEGG: D02497
• RxNorm: 402365
• Wikipedia: Fosamprenavir
• TTD: D0F5MT
• LINCS BRD: BRD-K59110290

Synonyms

• fos-amprenavir
• GW433908
• GW-433908
• telzir
• amprenavir phosphate
• fosamprenavir calcium
• GW433908A
• Telzir
• Amprenavir phosphate
• Fosamprenavir [INN]
• GW 433908
• VX-175
• Fosamprenavir (INN)
• Lexiva (TM)
• Lexiva (TN)
• Telzir (TN)
• Telzir(TM)
• GW433908A (*Sodium Salt*)
• GW433908G (*Calcium Salt*)
• [(3S)-oxolan-3-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-1-phenyl-3-phosphonooxybutan-2-yl]carbamate
• Carbamic acid, ((1S,2R)-3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-1-(phenylmethyl)-2-(phosphonooxy)propyl)-, C-((3S)-tetrahydro-3-furanyl) ester
• ((3S)Oxolan-3-yloxy)-N-((1S,2R)-3-{[(4-aminophenyl)sulfonyl](2-methylpropyl)amino}-1-benzyl-2-(phosphonooxy)propyl)carboxamide
• (3-(((4-Aminophenyl)sulfonyl)(2-methylpropyl)amino)-1-(phenylmethyl)-2-(phosphonooxy)propyl)carbamic acid C-(tetrahydro-3-furanyl) ester
• FOS-APV
• WOU1621EEG
• CHEBI:82941
• GW-908
• fosamprenavirum
• RefChem:921785
• DTXCID7028271
• C25H36N3O9PS
• HSDB 7340
• UNII-WOU1621EEG
• MFCD09955118
• GW908 cpd
• VX175 cpd
• FOSAMPRENAVIR [MI]
• Epitope ID:231725

Reported adverse events

• Angioedema
• Fatigue
• Headache
• Nausea
• Rash
• Vomiting
• Abdominal pain
• Myocardial infarction
• Nephrolithiasis