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LEUCOVORIN

SynDRA canonical compound SYN0018573 — structure-anchored drug synonym record

All known targets

• DHFR
• TYMS

Mechanisms of action (all sources)

• folate receptor ligand
• DHFR MODULATOR

Drug classes

• Antidotes
• Micronutrients
• Protective Agents
• Vitamin B Complex
• Vitamins
• Folate Analog

ATC classes

• V03A · ALL OTHER THERAPEUTIC PRODUCTS

Cross-references

• PubChem CID: 135403648
• ChEMBL: CHEMBL1679
• DrugBank: DB00650
• ChEBI: CHEBI:15640
• KEGG: D01211
• RxNorm: 6313
• Wikipedia: Folinic_acid
• TTD: D0B6TW
• LINCS BRD: BRD-A75919782

Synonyms

• sodium folinate
• folinic acid
• calcium folinate
• leucovorin calcium
• folinic acid calcium salt
• folinic acid calcium
• wellcovorin
• folinic acid calcium salt pentahydrate
• Folinic acid
• 5-formyltetrahydrofolate
• 5-formyltetrahydrofolic acid
• Leucovorin Calcium
• Leucovorin Calcium Preservative Free
• Wellcovorin
• 5-Formyltetrahydrofolic acid
• Folinic acid-SF
• Welcovorin
• Acide folinique
• 5-Formyl-5,6,7,8-tetrahydrofolic acid
• folinate
• N5-Formyltetrahydrofolic acid
• 10-Formyl-7,8-dihydrofolic acid
• Leucal
• N5-Formyl-5,6,7,8-tetrahydrofolic acid
• Q573I9DVLP
• 5-Formyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid
• CHEBI:15640
• (5-formyl-5,6,7,8-tetrahydropteroyl)glutamate
• L-Glutamic acid, N-(4-(((2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-
• HSDB 6544
• N-(5-formyl-5,6,7,8-tetrahydropteroyl)-L-glutamic acid
• Leucoverin
• [3H]folinic acid
• NSC3590
• Leucovorinum (acid)
• Leucovorin [USAN]
• CHEMBL69905
• UNII-Q573I9DVLP

Reported adverse events

• Nausea
• Stomatitis
• Vomiting
• Constipation
• Dermatitis
• Malaise
• Leukopenia
• Alopecia
• Fatigue
• Infection
• Lethargy
• Thrombocytopenia