NINTEDANIB

SynDRA canonical compound SYN0018962 — structure-anchored drug synonym record

Clinical phase	Launched
Approval status	Approved · Rx
Primary target(s)	FGFR1 \| FGFR2 \| FGFR3 \| FGFR4 \| FLT1 \| FLT4 \| KDR \| LYN \| PDGFRA \| PDGFRB
Mechanism of action	FGFR inhibitor \| PDGFR tyrosine kinase receptor inhibitor \| VEGFR inhibitor
Indication	idiopathic pulmonary fibrosis (IPF)
Disease area	pulmonary

All known targets

BIBF1120
nibtedanib
nintedanib esylate
intedanib
BIBF 1120
ofev
nintedanib ethanesulfonate
vargatef
Intedanib
BIBF-1120
Nintedanib component of ofev
Ofev
Vargatef
Nintedanib (BIBF 1120)
OFEV
UNII-G6HRD2P839
(Z)-methyl 3-((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenylamino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
G6HRD2P839
CHEBI:85164
Methyl (3z)-3-{[(4-{methyl[(4-Methylpiperazin-1-Yl)acetyl]amino}phenyl)amino](Phenyl)methylidene}-2-Oxo-2,3-Dihydro-1h-Indole-6-Carboxylate
CID 9809715
Methyl (3Z)-3-[[4-[methyl-[2-(4-methylpiperazin-1-yl)acetyl]amino]anilino]-phenylmethylidene]-2-oxo-1H-indole-6-carboxylate
(Z)-Methyl 3-((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)-phenylamino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
Methyl (3Z)-3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylidene)-2-oxo-2,3-dihydro-1h-indole-6-carboxylate
methyl (3Z)-3-[({4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]phenyl}amino)(phenyl)methylidene]-2-oxo-2,3-dihydro-1H-indole-6-carboxylate
methyl 2-hydroxy-3-[N-[4-[methyl-[2-(4-methylpiperazin-1-yl)acetyl]amino]phenyl]-C-phenylcarbonimidoyl]-1H-indole-6-carboxylate
methyl (3Z)-3-[(4-{methyl[(4-methylpiperazin-1-yl)acetyl]amino}anilino)(phenyl)methylidene]-2-oxo-2,3-dihydro-1H-indole-6-carboxylate
Nintedanib [INN]
Nintedanib [USAN]
Nintedanib [USAN:INN]
BIBF1120 (Vargatef)
Vargatef Base
Nintedanib- Bio-X
Nintedanib, Free Base
BIBF1120,Vargatef
Nintedanib (Intedanib)
INTEDANIB [MI]
Bibf1120 - Vargatef