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MILCICLIB
SynDRA canonical compound SYN0019550 — structure-anchored drug synonym record
| Clinical phase | Phase 2 |
|---|
| Primary target(s) | CDK1 |
|---|
| Mechanism of action | Growth factor receptor inhibitor |
|---|
All known targets
- CDK2
- CDK1
- CDK4
- NTRK1
- CDK5
- CDK7
- CDK9
Mechanisms of action (all sources)
- cyclin-dependent kinase inhibitor
- Growth factor receptor inhibitor
- CDK1 INHIBITOR
- Cyclin-dependent kinase 1 inhibitor
- CDK2 INHIBITOR
- Cyclin-dependent kinase 2 inhibitor
- CDK4/6 inhibitor
- Cyclin-dependent kinase 4 inhibitor
- NTRK1 INHIBITOR
- Nerve growth factor receptor Trk-A inhibitor
- CDK5 INHIBITOR
- CDK7 INHIBITOR
Cross-references
Synonyms
- PHA-848125
- PHA848125
- PHA 848125
- Milciclib (PHA-848125)
- UNII-688000M8S8
- MMV676602
- 4,5-dihydro-N,1,4,4-tetramethyl-8-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-1H-Pyrazolo[4,3-h]quinazoline-3-carboxamide
- 688000M8S8
- N,1,4,4-tetramethyl-8-(4-(4-methylpiperazin-1-yl)phenylamino)-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide
- Milciclib [INN]
- N,1,4,4-Tetramethyl-8-{[4-(4-Methylpiperazin-1-Yl)phenyl]amino}-4,5-Dihydro-1h-Pyrazolo[4,3-H]quinazoline-3-Carboxamide
- RefChem:926384
- C25H32N8O
- P48
- MFCD17169990
- Milciclib; PHA 848125
- MLS006011032
- PHA-848125(Milciclib)
- SCHEMBL619139
- GTPL7938
- orb1301090
- BDBM31545
- RXZMYLDMFYNEIM-UHFFFAOYSA-N
- GLXC-90288
- HMS3656P21
- EX-A2135
- NSC800792
- s2751
- AKOS030231455
- CCG-269340
- CS-0579
- NSC-800792
- SB16657
- SDCCGSBI-0654461.P001
- NCGC00346673-01
- NCGC00346673-05
- NCGC00346673-09
- AC-35945
- AS-56203
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