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DEFERASIROX

SynDRA canonical compound SYN0019839 — structure-anchored drug synonym record

All known targets

• CYP3A4
• BLVRB
• CYP2C19
• CYP2C8
• KDM5A

Mechanisms of action (all sources)

• Chelating agent

Drug classes

• Iron Chelating Activity
• Iron Chelator
• Chelating Agents
• Iron Chelating Agents
• Sequestering Agents
• Cytochrome P450 1A2 Inhibitors
• Cytochrome P450 3A4 Inducers
• Cytochrome P450 2C8 Inhibitors

ATC classes

• V03A · ALL OTHER THERAPEUTIC PRODUCTS

Cross-references

• PubChem CID: 214348
• ChEMBL: CHEMBL550348
• DrugBank: DB01609
• ChEBI: CHEBI:49005
• KEGG: D03669
• RxNorm: 614373
• PDB: JBL
• Wikipedia: Deferasirox
• TTD: D0Q5UQ
• LINCS BRD: BRD-K97010173

Synonyms

• ICL670A
• ICL 670A
• exjade
• Osveral
• ICL-670
• ICL-670A
• ICL670
• Deferasirox accord
• Deferasirox mylan
• Exjade
• Jadenu
• Jadenu sprinkle
• Deferasiroxum
• Deferasiroxum [INN-Latin]
• 4-[3,5-Bis(2-hydroxyphenyl)-1,2,4-triazol-1-yl]benzoic acid
• Jadenu Sprinkle
• 4-[3,5-bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic acid
• 4-(3,5-Bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl)benzoic acid
• CGP-72670
• Deferasirox (Exjade)
• CHEBI:49005
• V8G4MOF2V9
• Benzoic acid, 4-[3,5-bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]-
• NCGC00181754-01
• Benzoic acid, 4-(3,5-bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl)-
• 4-[bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic acid
• SMR002544689
• CAS-201530-41-8
• UNII-V8G4MOF2V9
• Deferasirox [USAN:INN:JAN]
• HSDB 7844
• 4-(3,5-Bis(6-oxocyclohexa-2,4-dien-1-ylidene)-1,2,4-triazolidin-1-yl)benzoic acid
• 4-[3,5-bis(6-oxocyclohexa-2,4-dien-1-ylidene)-1,2,4-triazolidin-1-yl]benzoic acid
• Deferasirox [INN]
• Exjade (TN)
• Jadenu (TN)
• Deferasirox, ICL670
• DEFERASIROX [MI]

Reported adverse events

• Fanconi syndrome
• Hemorrhage
• Hypersensitivity
• Proteinuria
• Rash
• Stevens-Johnson syndrome
• Adverse reaction
• Abdominal pain
• Death
• Nausea
• Vomiting
• Injury