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UCN-01
SynDRA canonical compound SYN0020053 — structure-anchored drug synonym record
| Clinical phase | Phase 2 |
|---|
| Primary target(s) | CDK1 |
|---|
| Mechanism of action | PKC inhibitor |
|---|
All known targets
- CHEK1
- PDPK1
- CDK4
- PRKCA
- PRKCG
- PRKCD
- PRKCB
- CDK1
- PRKCE
- CHEK2
- CDK6
- CDK2
Mechanisms of action (all sources)
- cyclin-dependent kinase inhibitor
- CHK inhibitor
- PKC inhibitor
- CDK2 INHIBITOR
- Cyclin-dependent kinase 2 inhibitor
- CDK4/6 inhibitor
- Cyclin-dependent kinase 4 inhibitor
- Cyclin-dependent kinase 6 inhibitor
- CHEK1 INHIBITOR
- Serine/threonine-protein kinase Chk1 inhibitor
- PDPK1 INHIBITOR
- 3-phosphoinositide dependent protein kinase-1 inhibitor
Cross-references
Synonyms
- 7-hydroxystaurosporine
- KRX-0601
- KW-2401
- NSC-638850
- UCN-02
- Ucn 01
- UCN
- UCN01
- (5s,6r,7r,9r,16r)-16-hydroxy-6-methoxy-5-methyl-7-(methylamino)-6,7,8,9,15,16-hexahydro-5h,14h-5,9-epoxy-4b,9a,15-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacen-14-one
- 7-Hydroxystaurosporine
- 7-hydroxystaurosporine (UCN-01)
- 7-HYDROXYSTAUROSPORINE
- RefChem:933742
- UCN 02
- 7-epi-Hydroxystaurosporine
- orb1909246
- SCHEMBL16946789
- SCHEMBL29354706
- CHEBI:221846
- PBCZSGKMGDDXIJ-KRUBCLEUSA-N
- GLXC-15334
- HMS3229L19
- BDBM50280450
- NSC800958
- NSC-800958
- NCGC00346827-02
- NCGC00346827-03
- UCN-01, >=97% (HPLC), powder
- DA-68461
- HY-108262
- CS-0027882
- T17198
- BRD-K45293975-001-02-0
Look up UCN-01 in the interactive SynDRA portal →