← SynDRA

RAF-265

SynDRA canonical compound SYN0020056 — structure-anchored drug synonym record

All known targets

• BRAF
• KDR
• KIT
• PDGFRB
• RAF1

Mechanisms of action (all sources)

• BRAF INHIBITOR
• Serine/threonine-protein kinase B-raf inhibitor
• KDR INHIBITOR
• Vascular endothelial growth factor receptor 2 inhibitor
• RAF inhibitor
• VEGFR inhibitor
• KDR MODULATOR

Cross-references

• PubChem CID: 11656518
• ChEMBL: CHEMBL558752
• DrugBank: DB05984
• ChEBI: 91451
• PDB: 55J
• TTD: D03AND
• LINCS BRD: BRD-K93123848

Synonyms

• CHIR-265
• NVP-RAF265
• RAF265
• CHIR 265
• RAF265 (CHIR-265)
• 1-Methyl-5-[[2-[5-(trifluoromethyl)-1h-imidazol-2-yl]-4-pyridinyl]oxy]-n-[4-(trifluoromethyl)phenyl]-1h-benzimidazol-2-amine
• CHIR265
• RAF265(CHIR-265)
• UNII-8O434L3768
• 8O434L3768
• 1-methyl-5-[2-[5-(trifluoromethyl)-1H-imidazol-2-yl]pyridin-4-yl]oxy-N-[4-(trifluoromethyl)phenyl]benzimidazol-2-amine
• 1-Methyl-5-({2-[5-(Trifluoromethyl)-1h-Imidazol-2-Yl]pyridin-4-Yl}oxy)-N-[4-(Trifluoromethyl)phenyl]-1h-Benzimidazol-2-Amine
• PubChem22594
• RAF 265
• RAF-265 (CHIR-265)
• 1-Methyl-5-((2-(5-(trifluoromethyl)-1H-imidazol-2-yl)-4-pyridinyl)oxy)-N-(4-(trifluoromethyl)phenyl)-1H-benzimidazol-2-amine
• 1-Methyl-5-[[2-[5-(trifluoromethyl)-1H-imidazol-2-yl]-4-pyridinyl]-oxy]-N-[4-(trifluoromethyl)phenyl]-1H-benzimidazol-2-amine
• SCHEMBL686452
• CHEMBL558752
• GTPL5674
• RAF 265 [WHO-DD]
• BDBM31088
• CHEBI:91451
• EX-A072
• cid_11656518
• DTXSID601025871
• HMS3655B06
• HMS3672I21
• AMY24172
• RAF265 - CHIR-265
• MFCD16659061
• NSC754357
• NSC800861
• s2161
• ZINC18710085
• CHIR 265 (RAF 265)
• AKOS025117575
• CCG-264703