← SynDRA

QUIZARTINIB

SynDRA canonical compound SYN0020171 — structure-anchored drug synonym record

All known targets

• FLT3
• CSF1R
• KIT
• RET
• PDGFRB
• PDGFRA
• NTRK2
• MUSK
• MYH10
• MYLK
• MYLK3
• NTRK1

Mechanisms of action (all sources)

• FLT3 INHIBITOR
• CSF1R INHIBITOR
• Macrophage colony stimulating factor receptor inhibitor
• Tyrosine-protein kinase receptor FLT3 inhibitor
• KIT INHIBITOR
• Stem cell growth factor receptor inhibitor
• PDGFRB INHIBITOR
• Platelet-derived growth factor receptor inhibitor
• PDGFRA INHIBITOR
• RET INHIBITOR
• Tyrosine-protein kinase receptor RET inhibitor

Drug classes

• Antineoplastic Agents
• Tyrosine Kinase Inhibitors

ATC classes

• L01E · PROTEIN KINASE INHIBITORS

Cross-references

• PubChem CID: 24889392
• ChEMBL: CHEMBL576982
• DrugBank: DB12874
• ChEBI: CHEBI:90217
• KEGG: D09956
• RxNorm: 2643048
• PDB: P30
• Wikipedia: Quizartinib
• TTD: D07KYT
• LINCS BRD: BRD-K93918653

Synonyms

• quizartinib hydrochloride
• quizartinib dihydrochloride
• vanflyta
• AC220
• AC010220
• AC-220
• AC-010220
• AC010220.2HCL
• AC220 (QUIZARTINIB)
• AC708
• ASP-2689
• QUIZARTINIB (AC220)
• Quizartinib dihydrochloride
• Quizartinib (AC220)
• AC 220
• Quizartinib HCl
• Quizartinib freebase
• 1-(5-(tert-butyl)isoxazol-3-yl)-3-(4-(7-(2-morpholinoethoxy)benzo[d]imidazo[2,1-b]thiazol-2-yl)phenyl)urea
• 7LA4O6Q0D3
• CHEMBL576982
• N-(5-tert-Butylisoxazol-3-yl)-N'-{4-[7-(2-morpholin-4-ylethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea
• CHEBI:90217
• 950769-58-1 (free base)
• 1132827-21-4 (HCl)
• 1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morpholin-4-Yl)ethoxy]imidazo[2,1-B][1,3]benzothiazol-2-Yl}phenyl)urea
• 1-(5-tert-butyl-1,2-oxazol-3-yl)-3-[4-[6-(2-morpholin-4-ylethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl]urea
• n-(5-tert-butyl-isoxazol-3-yl)-n'-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea dihydrochloride
• CHEMBL2386811
• 1-(5-(tert-Butyl)isoxazol-3-yl)-3-(4-(7-(2-morpholinoethoxy)-benzo[d]imidazo[2,1-b]thiazol-2-yl)phenyl)urea
• N-(5-(1,1-Dimethylethyl)isoxazol-3-yl)-N'-(4-(7-(2-(morpholin-4-yl)ethoxy)imidazo(2,1-b)benzothiazol-2-yl)phenyl)urea
• Urea, N-(5-(1,1-dimethylethyl)-3-isoxazolyl)-N'-(4-(7-(2-(4-morpholinyl)ethoxy) imidazo(2,1-b)benzothiazol-2-yl)phenyl)-
• AC220 compound
• AC220,Quizartinib
• Quizartinib [USAN]
• Quizartinib [USAN:INN]
• quizartinibum
• UNII-7LA4O6Q0D3
• 1-(5-TERT-BUTYL-1,2-OXAZOL-3-YL)-3-(4-(7-(2-(MORPHOLIN-4-YL)ETHOXY)IMIDAZO(2,1-B)(1,3)BENZOTHIAZOL-2-YL)PHENYL)UREA