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AEE-788
SynDRA canonical compound SYN0020328 — structure-anchored drug synonym record
| Clinical phase | Phase 1/Phase 2 |
| Primary target(s) | EGFR | ERBB2 | ERBB4 | FGFR2 | FGFR3 | FLT1 | KDR |
| Mechanism of action | EGFR inhibitor | VEGFR inhibitor |
All known targets
- EGFR
- ERBB2
- FGFR2
- FGFR3
- FLT1
- KDR
- ERBB4
Mechanisms of action (all sources)
- EGFR INHIBITOR
- Epidermal growth factor receptor erbB1 inhibitor
- ERBB2 INHIBITOR
- Receptor protein-tyrosine kinase erbB-2 inhibitor
- KDR INHIBITOR
- Vascular endothelial growth factor receptor 2 inhibitor
- FLT1 INHIBITOR
- Vascular endothelial growth factor receptor 1 inhibitor
- VEGFR inhibitor
- FGFR2 INHIBITOR
- FGFR3 INHIBITOR
Cross-references
Synonyms
- AEE788
- GNF-PF-5343
- NVP-AEE-788
- NVP-AEE788
- AEE 788
- AEE
- GNF-Pf-5343
- AEE-788, NVP-AEE 788, AEE788
- AEE788 (NVP-AEE788)
- (R)-6-(4-((4-Ethylpiperazin-1-yl)methyl)phenyl)-N-(1-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
- F9JLR95I3I
- 6-{4-[(4-Ethylpiperazin-1-Yl)methyl]phenyl}-N-[(1r)-1-Phenylethyl]-7h-Pyrrolo[2,3-D]pyrimidin-4-Amine
- AEE-788 (NVP-AEE788)
- 6-[4-[(4-Ethyl-1-piperazinyl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
- 7H-pyrrolo(2,3-d)pyrimidin-4-amine, 6-(4-((4-ethyl-1-piperazinyl)methyl)phenyl)-N-((1R)-1-phenylethyl)-
- (R)-6-(4-((4-ethylpiperazin-1-yl)methyl)phenyl)-N-(1-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine.
- 6-[4-[(4-ethylpiperazin-1-yl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
- 7H-Pyrrolo[2,3-d]pyrimidin-4-amine,6-[4-[(4-ethyl-1-piperazinyl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-
- UNII-F9JLR95I3I
- 7h-pyrrolo[2,3-d]pyrimidin-4-amine,6-(4-((4-ethyl-1-piperazinyl)methyl)phenyl)-n-((1r)-1-phenylethyl)-
- MLS006011277
- SCHEMBL613756
- CHEMBL587723
- GTPL7643
- AEE 788 [WHO-DD]
- BDBM26105
- CHEBI:40629
- DTXSID90964400
- AEE788; NVP-AEE788
- BCPP000427
- EX-A2259
- MFCD11100351
- NSC765949
- NSC799325
- s1486
- ZINC22453679
- AKOS016011091
- BCP9000241
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