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DESOXIMETASONE
SynDRA canonical compound SYN0020349 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | NR3C1 | PLA2G1B |
|---|
| Mechanism of action | glucocorticoid receptor agonist |
|---|
| Indication | corticosteroid-responsive dermatoses |
|---|
| Disease area | dermatology |
|---|
All known targets
- NR3C1
- ANXA1
- ESRRA; ESRRB; ESRRG
- PGR
- PLA2G1B
Mechanisms of action (all sources)
Drug classes
- Corticosteroid Hormone Receptor Agonists
- Corticosteroid
- Anti-Inflammatory Agents
- Glucocorticoids
- Hormones
ATC classes
- D07A · CORTICOSTEROIDS, PLAIN
- D07X · CORTICOSTEROIDS, OTHER COMBINATIONS
Cross-references
Synonyms
- deoxymethasone
- desoximethasone
- desoxymetasone
- desoxymethasone
- Desoximetasona
- Desoxymethasone
- A-41-304
- A-41304
- HOE-304
- J83.644C
- NSC-759189
- R-2113
- Stiedex
- Stiedex lp
- Stiedex lpn
- Topicort
- Topicort lp
- Desoximetasonum
- Topicort (TN)
- Topicort Emollient (TN)
- Desoximetasone (USP/INN)
- (11beta,16alpha)-9-Fluoro-11,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione
- (8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-7,8,11,12,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthren-3-one
- 9-Fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione
- 9alpha-fluoro-16alpha-methyl-Delta(1)-corticosterone
- BRD-K30697463
- HOE 304
- desoximetasone (usp impurity)
- A 41304
- A 41-304
- 4E07GXB7AU
- desoximetasone (usp-rs)
- dexamethasone impurity f (ep impurity)
- NSC 759189
- R 2113
- desoximetasone (usp monograph)
- Topicort LP
- Desossimetasone
Reported adverse events
- Cushing's syndrome
- Perioral dermatitis
- Application site irritation
- Application site pruritus
- Application site dryness
- Milia
- Miliaria
- Hypertrichosis
- Skin atrophy
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