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LESTAURTINIB

SynDRA canonical compound SYN0020499 — structure-anchored drug synonym record

All known targets

• FLT3
• NTRK1
• JAK2
• NTRK2
• NTRK3
• RET

Mechanisms of action (all sources)

• JAK inhibitor
• FLT3 INHIBITOR
• Growth factor receptor inhibitor
• Tyrosine-protein kinase receptor FLT3 inhibitor
• JAK2 INHIBITOR
• Tyrosine-protein kinase JAK2 inhibitor
• NTRK1 INHIBITOR
• Nerve growth factor receptor Trk-A inhibitor
• NTRK2 INHIBITOR
• Neurotrophic tyrosine kinase receptor type 2 inhibitor
• NTRK3 INHIBITOR
• NT-3 growth factor receptor inhibitor

Cross-references

• PubChem CID: 126565
• ChEMBL: CHEMBL603469
• DrugBank: DB06469
• ChEBI: 91471
• KEGG: D04696
• PDB: 2V9
• Wikipedia: Lestaurtinib
• TTD: D0V9WF
• LINCS BRD: BRD-K23192422

Synonyms

• A-154475
• A-154475.0
• CEP-701
• KT-555
• KT-5555
• KT5555
• SP-924
• SP924
• SPM-924
• A 1544750
• SP 924
• Lestaurtinib (USAN/INN)
• CEP 701
• KT 5555
• CEP701
• C26H21N3O4
• CHEMBL603469
• DO989GC5D1
• A 154475.0
• (9S,10S,12R)-2,3,9,10,11,12-Hexahydro-10-hydroxy-10-(hydroxymethyl)-9-methyl-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocin-1-one
• NCGC00168772-01
• (5S,6S,8R)-6-hydroxy-6-(hydroxymethyl)-5-methyl-7,8,14,15-tetrahydro-5H-16-oxa-4b,8a,14-triaza-5,8-methanodibenzo[b,h]cycloocta[jkl]cyclopenta[e]-as-indacen-13(6H)-one
• Lestaurtinib [USAN]
• Lestaurtinib [USAN:INN]
• UNII-DO989GC5D1
• 4otg
• CEP-701 hydrate
• Lestaurtinib; CEP701
• LESTAURTINIB [INN]
• LESTAURTINIB [MART.]
• LESTAURTINIB [WHO-DD]
• GTPL5672
• SCHEMBL1649693
• DTXSID5046778
• CHEBI:91471
• 9,12-Epoxy-1H-diindolo(1,2,3-fg:3',2',1'-kl)pyrrolo(3,4-i)(1,6)benzodiazocin-1-one, 2,3,9,10,11,12-hexahydro-10-hydroxy-10-(hydroxymethyl)-9-methyl-, (9S,10S,12R)-
• 9,12-Epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocin-1-one, 2,3,9,10,11,12-hexahydro-10-hydroxy-10-(hydroxymethyl)-9-methyl-, (9S,10S,12R)-
• BCP06977