← SynDRA

VARENICLINE

SynDRA canonical compound SYN0021114 — structure-anchored drug synonym record

All known targets

• CHRNA4
• CHRNB2
• CHRNA7
• CHRNA3
• CHRNA1
• Chrna2
• Chrnb4
• Chrnb2
• Chrna7
• Chrna4
• Chrna3
• CHRND

Mechanisms of action (all sources)

• Acetylcholine receptor agonist
• CHRNB2 AGONIST
• Neuronal acetylcholine receptor; alpha4/beta2 agonist
• CHRNA4 AGONIST
• CHRNB2 PARTIAL AGONIST
• Neuronal acetylcholine receptor; alpha4/beta2 partial agonist
• CHRNA4 PARTIAL AGONIST
• Modulator

Drug classes

• Cholinergic Agonists
• Cholinergic Agents
• Neurotransmitter Agents
• Nicotinic Agonists
• Smoking Cessation Agents
• Partial Cholinergic Nicotinic Agonists
• Partial Cholinergic Nicotinic Agonist
• Cholinergic Receptor Agonist

ATC classes

• N07B · DRUGS USED IN ADDICTIVE DISORDERS
• S01X · OTHER OPHTHALMOLOGICALS

Cross-references

• PubChem CID: 170361
• ChEMBL: CHEMBL1396
• DrugBank: DB01273
• ChEBI: CHEBI:84500
• KEGG: D06282
• RxNorm: 591622
• PDB: QMR
• Wikipedia: Varenicline
• TTD: D0LM4A
• LINCS BRD: BRD-K18855837

Synonyms

• champix
• chantix
• varenicline tartrate
• CP-526,555-18
• Vareniclina
• CP-526,555
• CP-526555
• CP 526555
• Champix (TN)
• Chantix (TN)
• Varenicline (INN)
• 7,8,9,10-Tetrahydro-6,10-methano-6H-pyrazino(2,3-h)(3)benzazepine
• 7,8,9,10-tetrahydro-6h-6,10-methanoazepino[4,5-g]quinoxaline
• 7,8,9,10-TETRAHYDRO-6H-6,10-METHANOAZEPINO(4,5-G)QUINOXALINE
• W6HS99O8ZO
• vareniclina
• vareniclinum
• CHEBI:84500
• RefChem:58779
• DTXCID80197326
• N07BA03
• DTXCID101030560
• VARENICLINE [INN]
• Varenicline [INN:BAN]
• UNII-W6HS99O8ZO
• Champix;
• HSDB 7591
• MFCD10001497
• Varenicline Impurity 38
• VARENICLINE [MI]
• VARENICLINE [HSDB]
• VARENICLINE [VANDF]
• VARENICLINE [MART.]
• US9284322, varenicline
• VARENICLINE [WHO-DD]
• SCHEMBL137144
• VARENICLINE [EMA EPAR]
• GTPL5459

Reported adverse events

• Depression
• Depressed mood
• Nausea
• Headache
• Hypersensitivity
• Rash
• Somnolence
• Angioedema
• Abnormal dreams
• Asthenia
• Constipation
• Dysgeusia