← SynDRA

GSK-1070916

SynDRA canonical compound SYN0021725 — structure-anchored drug synonym record

All known targets

• AURKB
• AURKC
• AURKA
• CYP2D6
• CYP3A4

Mechanisms of action (all sources)

• aurora kinase inhibitor
• AURKB INHIBITOR
• Serine/threonine-protein kinase Aurora-B inhibitor
• AURKC INHIBITOR
• Serine/threonine-protein kinase Aurora-C inhibitor
• AURKA INHIBITOR
• AURKB MODULATOR
• AURKC MODULATOR

Cross-references

• PubChem CID: 46885626
• ChEMBL: CHEMBL1090479
• ChEBI: 91362
• TTD: D0IQ0Z
• LINCS BRD: BRD-K36740062

Synonyms

• GSK 1070916A
• GSK1070916
• GSK1070916A
• GSK 1070916
• 3-(4-(4-(2-(3-((dimethylamino)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)-1-ethyl-1H-pyrazol-3-yl)phenyl)-1,1-dimethylurea
• 8VLB51V7HO
• N'-[4-[4-[2-[3-[(Dimethylamino)methyl]phenyl]-1H-pyrrolo[2,3-b]pyridin-4-yl]-1-ethyl-1H-pyrazol-3-yl]phenyl]-N,N-dimethylurea
• CHEMBL1090479
• 3-[4-[4-[2-[3-[(dimethylamino)methyl]phenyl]-1H-pyrrolo[2,3-b]pyridin-4-yl]-1-ethylpyrazol-3-yl]phenyl]-1,1-dimethylurea
• 3-(4-(4-(2-(3-((dimethylamino)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)-1-ethyl-1H-pyrazol-3-yl)phenyl)-1,1-dimethylurea.
• UNII-8VLB51V7HO
• 3-(4-(4-(2-(3-((DIMETHYLAMINO)METHYL)PHENYL)-1H-PYRROLO(2,3-B)PYRIDIN-4-YL)-1-ETHYL-1H-PYRAZOL-3-YL)PHENYL)-1,1-DIMETHYLUREA
• N'-{4-[4-(2-{3-[(dimethylamino)methyl]phenyl}-1H-pyrrolo[2,3-b]pyridin-4-yl) 1-ethyl-1H-pyrazol-3-yl]phenyl}-N,N-dimethylurea
• compound 17k [PMID 20420387]
• GTPL8358
• SCHEMBL4305006
• CHEBI:91362
• DTXSID70241403
• EX-A021
• HMS3265K13
• HMS3265K14
• HMS3265L13
• HMS3265L14
• HMS3750K05
• ACT06827
• BCP02610
• BDBM50315769
• MFCD22420815
• NSC777445
• NSC800108
• s2740
• ZINC43170519
• AKOS005145558
• BCP9000733
• CCG-269759
• CS-0008
• NSC-777445
• NSC-800108