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FLUDARABINE PHOSPHATE
SynDRA canonical compound SYN0021754 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | RRM1 |
|---|
| Mechanism of action | DNA repair enzyme inhibitor |
|---|
| Indication | chronic lymphocytic leukemia (CLL) |
|---|
| Disease area | hematologic malignancy |
|---|
All known targets
- POLA1
- RRM1
- POLE
- RRM2
- POLD1
- Adora1
- PRIM2
- PRIM1
- POLE3
- POLE2
- POLD4
- Adora2a
Mechanisms of action (all sources)
- Purine antagonist
- DNA synthesis inhibitor
- DNA repair enzyme inhibitor
- POLA1 INHIBITOR
- DNA polymerase (alpha/delta/epsilon) inhibitor
- POLD4 INHIBITOR
- POLD3 INHIBITOR
- POLD1 INHIBITOR
- POLD2 INHIBITOR
- POLE INHIBITOR
- POLA2 INHIBITOR
- PRIM1 INHIBITOR
Drug classes
- Nucleic Acid Synthesis Inhibitors
- Antineoplastic Agents
- Antimetabolites
- Antimetabolites, Antineoplastic
- Immunologic Factors
- Immunosuppressive Agents
- Noxae
- Nucleoside Metabolic Inhibitor
ATC classes
Cross-references
Synonyms
- fludarabine 5'-monophosphate
- fludura
- fludara
- 2-F-ara-AMP
- Fludarabine 5'-monophosphate
- 2-f-ara-amp
- Fludarabine monophosphate
- NSC-312887
- NSC-328002
- Fludara
- Oforta
- Gedeptin
- Fludura
- 2-Fluoro-ARA AMP
- Fludarabine (phosphate)
- FAMP
- UNII-1X9VK9O1SC
- NSC 312887
- C10H13FN5O7P
- 2-Fluoro-9-(5-O-phosphono-beta-D-arabinofuranosyl)-9H-purin-6-amine
- 2-Fluoroadenine arabinoside 5'-monophosphate
- NSC 328002
- 1X9VK9O1SC
- 9-beta-Arabinofuranosyl-2-fluoroadenine-5'-phosphate
- Fludarabine Phosphate (Fludara)
- 9-beta-D-Arabinofuranosyl-2-fluoroadenine 5'-monophosphate
- CHEBI:63599
- 9-beta-D-Arab
- fludarabine-phosphate
- Fludarabine
- F-Ara-A
- (2R,3S,4S,5R)-2-(6-Amino-2-fluoro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
- 2-FLUORO-ARA-A
- Fludarabine [INN]
- 9-beta-D-Arabinofuranosyl-2-fluoroadenine
- Fludarabinum
- NSC-118218
- 2-F-ara-A
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