TRICLABENDAZOLE

SynDRA canonical compound SYN0022228 — structure-anchored drug synonym record

Clinical phase	Launched
Approval status	Approved · Rx
Primary target(s)	DNMT1
Mechanism of action	Microtubule inhibitor
Indication	tapeworm
Disease area	infectious disease

All known targets

DNMT1
TTR
Trypano CYSP

Mechanisms of action (all sources)

microtubule inhibitor
Inhibitor

Drug classes

Anthelmintic
Anthelmintics
Anti-Infective Agents
Antiparasitic Agents
Antiplatyhelmintic Agents
Cytochrome P450 2D6 Inhibitors
Cytochrome P450 1A2 Inhibitors
Cytochrome P450 2B6 Inhibitors
Cytochrome P450 2C19 Inhibitors
Cytochrome P450 2C9 Inhibitors
Cytochrome P450 2C8 Inhibitors
Cytochrome P450 3A Inhibitors

ATC classes

P02B · ANTITREMATODALS

Cross-references

PubChem CID: 50248
ChEMBL: CHEMBL1086440
DrugBank: DB12245
ChEBI: CHEBI:94759
KEGG: D07364
RxNorm: 2118525
PDB: JA9
Wikipedia: Triclabendazole
TTD: D02VMJ
LINCS BRD: BRD-K81916719

Synonyms

egaten
fasinex
Triclabendazol
Fasinex
EGA230B
NSC-759250
NVP-EGA230
Egaten
Egaten tm
6-Chloro-5-(2,3-dichlorophenoxy)-2-(methylthio)-1H-benzo[d]imidazole
C14H9Cl3N2OS
Triclabendazolum [INN-Latin]
Triclabendazol [INN-Spanish]
CCRIS 8988
UNII-4784C8E03O
CGA 89317
5-Chloro-6-(2,3-dichlorophenoxy)-2-(methylthio)-1H-benzimidazole
CPD000466357
MLS001424101
CHEMBL1086440
6-Chloro-5-(2,3-dichlorophenoxy)-2-methylthio-benzimidazole
4784C8E03O
NCGC00164610-01
Triclabendazole, 98%
SMR000466357
AK-68238
5-Chloro-6-(2,3-dichlorophenoxy)-2-(methylthio)benzimidazole
Triclabendazolum
6-chloro-5-(2,3-dichlorophenoxy)-2-methylsulfanyl-1H-benzimidazole
NSC 759250
1H-Benzimidazole, 6-chloro-5-(2,3-dichlorophenoxy)-2-(methylthio)-
CGA89317
6-chloro-5-(2,3-dichlorophenoxy)-2-(methylthio)-1H-benzimidazole
6-[2,3-bis(chloranyl)phenoxy]-5-chloranyl-2-methylsulfanyl-1H-benzimidazole
5-CHLORO-6-(2,3-DICHLOROPHENOXY)-2-(METHYLSULFANYL)-1H-1,3-BENZODIAZOLE
CGA-89317
5-chloro-6-(2,3-dichlorophenoxy)-2-methylsulfanyl-1H-benzimidazole

Reported adverse events

Abdominal pain
Abdominal pain upper
Asthenia
Chest discomfort
Chest pain
Cough
Headache
Hyperhidrosis
Jaundice
Nausea
Pruritus
Pyrexia

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