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ENZALUTAMIDE

SynDRA canonical compound SYN0022231 — structure-anchored drug synonym record

All known targets

• AR
• CYP2C19
• CYP2C8
• CYP3A4
• KLK3
• NR3C1

Mechanisms of action (all sources)

• AR ANTAGONIST
• AR MODULATOR

Drug classes

• Androgen Receptor Antagonists
• Androgen Receptor Inhibitor
• Cytochrome P450 3A4 Inducers
• Cytochrome P450 2C9 Inducers
• Cytochrome P450 2C19 Inducers

ATC classes

• L02B · HORMONE ANTAGONISTS AND RELATED AGENTS

Cross-references

• PubChem CID: 15951529
• ChEMBL: CHEMBL1082407
• DrugBank: DB08899
• ChEBI: CHEBI:68534
• KEGG: D10218
• RxNorm: 1307298
• Wikipedia: Enzalutamide
• TTD: D0QK5X
• LINCS BRD: BRD-K56851771

Synonyms

• xtandi
• MDV3100
• MDV-3100
• Enzalutamida
• Xtandi
• Enzalutamide (AR inhibitor)
• MDV 3100
• 4-(3-(4-cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide
• Enzalutamide (MDV3100)
• XTANDI
• MDV3100 (Enzalutamide)
• 93T0T9GKNU
• CHEBI:68534
• 4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]-2-fluoro-N-methylbenzamide
• 4-{3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl}-2-fluoro-N-methylbenzamide
• 4-{3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl}-2-fluoro-N-methylbenzamide
• Benzamide, 4-(3-(4-cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl)-2-fluoro-N-methyl-
• Enzalutamide [USAN]
• Enzalutamide [USAN:INN]
• UNII-93T0T9GKNU
• Xtandi (TN)
• ENZALUTAMIDE [MI]
• Enzalutamide; MDV3100
• Enzalutamide (JAN/USAN)
• ENZALUTAMIDE [INN]
• ENZALUTAMIDE [JAN]
• MDV3100, AldrichCPR
• ENZALUTAMIDE [VANDF]
• MLS006010067
• ENZALUTAMIDE [WHO-DD]
• SCHEMBL189749
• GTPL6812
• CHEMBL1082407
• DTXSID10912307
• EX-A046
• BCPP000169
• ENZALUTAMIDE [ORANGE BOOK]
• HMS3654L07

Reported adverse events

• Breast tenderness
• Dysphagia
• Hypersensitivity
• Pain
• Seizure
• Anxiety
• Arthralgia
• Choking
• Constipation
• Dizziness
• Dysgeusia
• Epistaxis