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RUCAPARIB
SynDRA canonical compound SYN0022765 — structure-anchored drug synonym record
| Clinical phase | Phase 3 |
|---|
| Approval status | Approved · Rx |
|---|
| Primary target(s) | PARP1 |
|---|
| Mechanism of action | PARP inhibitor |
|---|
All known targets
- PARP1
- PARP2
- PARP3
- PARP10
- PARP12
- PARP14
- PARP15
- PARP16
- PARP4
- TNKS
- TNKS2
Mechanisms of action (all sources)
- PARP inhibitor
- PARP1 INHIBITOR
- PARP 1, 2 and 3 inhibitor
- PARP3 INHIBITOR
- PARP2 INHIBITOR
Drug classes
- Antineoplastic Agents
- Enzyme Inhibitors
- Poly(ADP-ribose) Polymerase Inhibitors
- Poly(ADP-Ribose) Polymerase Inhibitors
- Poly(ADP-Ribose) Polymerase Inhibitor
ATC classes
- L01X · OTHER ANTINEOPLASTIC AGENTS
Cross-references
Synonyms
- rucaparib camsylate
- AG-14447
- rucaparib phosphate
- AG-14699
- AG014699
- PF01367338
- PF-1367338-BW
- CO-338
- rubraca
- rucaparib camphorsulfonate
- Rubraca
- UNII-8237F3U7EH
- 8237F3U7EH
- AK317822
- 8-Fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-6H-pyrrolo[4,3,2-ef][2]benzazepin-6-one
- 8-FLUORO-2-(4-((METHYLAMINO)METHYL)PHENYL)-4,5-DIHYDRO-1H-AZEPINO[5,4,3-CD]INDOL-6(3H)-ONE
- 6H-Pyrrolo[4,3,2-ef][2]benzazepin-6-one,8-fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-
- 8-fluoro-2-(4-methylaminomethyl-phenyl)-1,3,4,5-tetrahydro-azepino[5,4,3-cd]indol-6-one
- CHEBI:134689
- rucaparibum
- RefChem:57180
- DTXCID50105054
- L01XX55
- Rucaparib free base
- Rucaparib [INN]
- Kinome_3180
- Rucaparib [USAN:INN]
- RPB
- MFCD11977252
- RUCAPARIB [MI]
- Rucaparib (USAN/INN)
- RUCAPARIB [USAN]
- RUCAPARIB [WHO-DD]
- SCHEMBL844585
- Rucaparib(AG-014447)?
- GTPL7736
- orb1302838
- SCHEMBL29351768
Reported adverse events
- Abdominal pain
- Dizziness
- Dysgeusia
- Fatigue
- Nausea
- Neutropenia
- Photosensitivity reaction
- Rash
- Stomatitis
- Thrombocytopenia
- Vomiting
- Decreased appetite
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