← SynDRA
METHYLNALTREXONE
SynDRA canonical compound SYN0022843 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | OPRD1 | OPRK1 | OPRM1 |
|---|
| Mechanism of action | opioid receptor antagonist |
|---|
| Indication | constipation |
|---|
| Disease area | gastroenterology |
|---|
All known targets
- OPRM1
- OPRD1
- OPRK1
- CYP2D6
- MC4R
Mechanisms of action (all sources)
- OPRM1 ANTAGONIST
- Mu opioid receptor antagonist
- opioid receptor antagonist
- MC4R AGONIST
- OPRM1 MODULATOR
Drug classes
- Opioid Antagonists
- Central Nervous System Agents
- Narcotic Antagonists
- Peripheral Nervous System Agents
- Sensory System Agents
- Opioid Antagonist
ATC classes
- A06A · DRUGS FOR CONSTIPATION
Cross-references
Synonyms
- relistor
- methylnaltrexonium
- methylnaltrexone bromide
- Methylnaltrexone cation
- Methylnaltrexone ion
- MRZ-2663
- Methylnaltrexone bromide
- Relistor
- Methylnaltrexone (Bromide)
- Naltrexone methobromide
- N-Methylnaltrexone Bromide
- MRZ 2663BR
- N-Cyclopropylmethyl-noroxymorphone Methobromide
- MNTX
- C21H26NO4Br
- MOA-728
- Relistor (TN)
- Naltrexone Methyl Bromide
- N-Methyl Naltrexone Bromide
- MNTX-302
- SCHEMBL2798188
- CHEMBL1201770
- IFGIYSGOEZJNBE-KNLJMPJLSA-N
- ONO-3849
- Methylnaltrexone bromide (JAN/USAN)
- 3844AH
- AKOS015896214
- CS-0762
- AN-37324
- HY-75766
- Methylnaltrexone bromide, >
- W-5330
- CHIR-01020
- 0RK7M7IABE
- MRZ 2663
- Naltrexone MB
- Quaternary ammonium naltrexone
- RefChem:56829
Reported adverse events
- Abdominal pain
- Anxiety
- Chills
- Dizziness
- Flatulence
- Gastrointestinal perforation
- Headache
- Hyperhidrosis
- Nausea
- Tremor
- Vomiting
Look up METHYLNALTREXONE in the interactive SynDRA portal →