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EXEMESTANE
SynDRA canonical compound SYN0022945 — structure-anchored drug synonym record
| Clinical phase | Launched |
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| Approval status | Approved · Rx/OTC |
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| Primary target(s) | CYP19A1 |
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| Mechanism of action | Aromatase inhibitor |
|---|
| Indication | breast cancer |
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| Disease area | oncology |
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All known targets
Mechanisms of action (all sources)
- Aromatase inhibitor
- CYP19A1 INHIBITOR
- Cytochrome P450 19A1 inhibitor
Drug classes
- Aromatase Inhibitors
- Aromatase Inhibitor
- Antineoplastic Agents
- Enzyme Inhibitors
- Estrogen Antagonists
- Hormone Antagonists
- Steroid Synthesis Inhibitors
ATC classes
- L02B · HORMONE ANTAGONISTS AND RELATED AGENTS
Cross-references
Synonyms
- aromasine
- FCE 24304
- aromasin
- Exemestano
- FCE-24304
- FCE24304
- NSC-758907
- PNU-155971
- Aromasin
- Aromasil
- Aromasine
- EXE
- Exemestance
- Exemestanum
- Nikidess
- Pfizer brand of exemestane
- Curator_000009
- Aromasin (TN)
- Aromasin, Exemestane
- Exemestano [INN-Spanish]
- Exemestanum [INN-Latin]
- Exemestane [USAN:INN:BAN]
- Exemestane (JAN/USP/INN)
- (8R,9S,10R,13S,14S)-10,13-dimethyl-6-methylidene-7,8,9,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,17-dione
- 6-Methylenandrosta-1,4-diene-3,17-dione
- 6-Methyleneandrosta-1,4-diene-3,17-dione
- 6-methylideneandrosta-1,4-diene-3,17-dione
- 6-Methylene-androsta-1,4-diene-3,17-dione
- Androsta-1,4-diene-3,17-dione, 6-methylene-
- PNU 155971
- NY22HMQ4BX
- Exemestane(FCE 24304)
- CHEBI:4953
- (8R,9S,10R,13S,14S)-10,13-dimethyl-6-methylene-7,8,9,10,11,12,13,14,15,16-decahydro-3H-cyclopenta[a]phenanthrene-3,17(6H)-dione
- (8R,9S,10R,13S,14S)-10,13-Dimethyl-6-methylene-7,8,9,11,12,13,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17(10H,14H)-dione
- NSC713563
- NSC 758907
Reported adverse events
- Abdominal pain
- Depression
- Dizziness
- Fatigue
- Headache
- Insomnia
- Nausea
- Pain
- Vomiting
- Hot flush
- Alopecia
- Anxiety
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