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TRILOSTANE
SynDRA canonical compound SYN0023268 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · OTC |
|---|
| Primary target(s) | ESR1 | ESR2 | HSD3B2 | JUN | NR3C1 |
|---|
| Mechanism of action | 3beta-hydroxy-delta5-steroid dehydrogenase inhibitor |
|---|
| Indication | Cushing's syndrome |
|---|
| Disease area | endocrinology |
|---|
All known targets
- HSD3B2
- ESR2
- ESR1
- JUN
- NR3C1
Mechanisms of action (all sources)
- HSD3B2 INHIBITOR
- 3-beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type II inhibitor
- 3beta-hydroxy-delta5-steroid dehydrogenase inhibitor
- ESR2 MODULATOR
Drug classes
- Abortifacient Agents
- Abortifacient Agents, Steroidal
- Antineoplastic Agents
- Enzyme Inhibitors
- Reproductive Control Agents
ATC classes
- H02C · ANTIADRENAL PREPARATIONS
Cross-references
Synonyms
- modrastane
- modrefen
- modrenal
- desopan
- Trilostano
- Desopan
- NSC-758904
- WIN 24,540
- WIN-24540
- Modrastane
- Modrenal
- Trilocur
- Trilorale
- Desopan (TN)
- Modrenal (TN)
- Vetoryl (TN)
- Vetoryl, Trilostane
- Win-24540
- Trilostane (JAN/USAN)
- (4alpha,5alpha,17beta)-3,17-dihydroxy-4,5-epoxyandrost-2-ene-2-carbonitrile
- 3,17beta-dihydroxy-4alpha,5-epoxy-5alpha-androst-2-ene-2-carbonitrile
- L0FPV48Q5R
- NSC 758904
- Win 24540
- Vetoryl
- Trilostanum
- CHEBI:32260
- DTXCID103706
- VETORYL CAPSULES
- RefChem:56170
- 4alpha,5-epoxy-17beta-hydroxy-3-oxoandrostane-2-carbonitrile
- 2Alpha-cyano-4alpha,5alpha-epoxyandrostan-17beta-ol-3-one
- 4,5-Epoxy-17-hydroxy-3-oxoandrostane-2-carbonitrile
- MFCD00199295
- CAS-13647-35-3
- Trilostanum [INN-Latin]
- Trilostano [INN-Spanish]
- UNII-L0FPV48Q5R
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