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LUBIPROSTONE

SynDRA canonical compound SYN0023421 — structure-anchored drug synonym record

All known targets

• CLCN2

Mechanisms of action (all sources)

• CLCN2 OPENER
• Chloride channel protein 2 opener
• chloride channel activator
• CLCN2 ACTIVATOR

Drug classes

• Chloride Channel Activators
• Chloride Channel Activator
• Chloride Channel Agonists
• Membrane Transport Modulators

ATC classes

• A06A · DRUGS FOR CONSTIPATION

Cross-references

• PubChem CID: 157920
• ChEMBL: CHEMBL1201134
• DrugBank: DB01046
• ChEBI: CHEBI:34945
• KEGG: D04790
• RxNorm: 623033
• Wikipedia: Lubiprostone
• TTD: D00CTS

Synonyms

• amitiza
• Lubiprostona
• Lubiprostone hemiketal
• RU-0211
• SPI-0211
• Amitiza
• Lubiprostone [USAN]
• RU0211
• SPI0211
• AMITIZA (TN)
• Amitiza, RU-0211, SPI-0211, Lubiprostone
• (-)-7-((2R,4aR,5R,7aR)-2-(1,1-Difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta (b)pyran-5-yl)heptanoic acid
• (-)-7-((2R,4aR,5R,7aR)-2-(1,1-Difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta(b)pyran-5-yl)heptanoic acid
• 7-((1R,4R,6R,9R)-4-(1,1-difluoropentyl)-4-hydroxy-8-oxo-5-oxabicyclo(4.3.0)non-9-yl)heptanoic acid
• 7-[(2R,4aR,5R,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxo-3,4,4a,5,7,7a-hexahydrocyclopenta[b]pyran-5-yl]heptanoic acid
• lubiprostona
• lubiprostonum
• Amitza
• RefChem:55521
• A06AX03
• Lubiprostone (hemiketal)
• MFCD20268389
• Amitiza (TN)
• Bicyclic lubiprostone
• Lubiprostone powder
• NCGC00183105-01
• Lubiprostone (ring open)
• LUBIPROSTONE [MI]
• Lubiprostone (hemiketal)?
• LUBIPROSTONE [INN]
• LUBIPROSTONE [JAN]
• LUBIPROSTONE [VANDF]
• LUBIPROSTONE [MART.]
• LUBIPROSTONE [WHO-DD]
• SCHEMBL217184
• GTPL4242
• Lubiprostone (JAN/USAN/INN)
• orb2564331

Reported adverse events

• Nausea
• Abdominal discomfort
• Abdominal distension
• Abdominal pain
• Chest discomfort
• Dizziness
• Dyspepsia
• Headache
• Vomiting
• Dry mouth
• Fatigue
• Flatulence