← SynDRA

TEMSIROLIMUS

SynDRA canonical compound SYN0023453 — structure-anchored drug synonym record

All known targets

• MTOR
• FKBP1A
• ABCB1
• FKBP3
• IFNAR2
• PTEN

Mechanisms of action (all sources)

• FKBP1A INHIBITOR
• FK506-binding protein 1A inhibitor
• MTOR inhibitor

Drug classes

• Protein Kinase Inhibitors
• Antineoplastic Agents
• Enzyme Inhibitors
• Immunologic Factors
• Immunosuppressive Agents
• MTOR Inhibitors
• Kinase Inhibitor
• mTOR Inhibitors
• mTOR Inhibitor Immunosuppressant
• Anti-Bacterial Agents
• Anti-Infective Agents
• Antibiotics, Antineoplastic

ATC classes

• L01E · PROTEIN KINASE INHIBITORS

Cross-references

• PubChem CID: 6918289
• ChEMBL: CHEMBL1201182
• DrugBank: DB06287
• ChEBI: CHEBI:79699
• KEGG: D06068
• RxNorm: 657797
• PDB: A4I
• TTD: D05NDR

Synonyms

• torisel
• temsorolimus
• CCI 779
• CCI-779
• Torisel
• Sifalimumab
• Cci 779
• CHEBI:79699
• Torisel (TN)
• 42-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate]rapamycin
• Temsirolimus (JAN/USAN/INN)
• DB06287
• C15182
• D06068
• J-524319
• (1R,2R,4S)-4-[(2R)-2-[(1R,9S,12S,15R,18R,19R,21R,23S,30S,32S,35R)-1,18-dihydroxy-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-2,3,10,14,20-pentaoxo-11,36-dioxa-4-azatricyclo[30.3.1.0
• {4,9}]hexatriaconta-16,24,26,28-tetraen-12-yl]propyl]-2-methoxycyclohexyl 3-hydroxy-2-(hydroxymethyl)-2-methylpropanoate
• 624KN6GM2T
• CHEMBL1201182
• NCGC00167518-01
• Rapamycin 42-(2,2-bis(hydroxymethyl)propionate)
• Rapamycin 42-[3-hydroxy-2-(hydroxymethyl)-2-methylpropanoate]
• Rapamycin, 42-(3-hydroxy-2-(hydroxymethyl)-2-methylpropanoate)
• (1R,2R,4S)-4-{(2R)-2-[(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,30S,34aS)-9,27-dihydroxy-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-1,5,11,28,29-pentaoxo-1,4,5,6,9,10,11,12,13,14,21,22,23,24,25,26,27,28,29,31,32,33,34,34a-tetracosahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontin-3-yl]propyl}-2-methoxycyclohexyl 3-hydroxy-2-(hydroxymethyl)-2-methylpropanoate
• Temserolimus
• NSC-683864
• MFCD00934421
• Temsirolimus (CCI-779, NSC 683864)
• Temsirolimus [USAN]
• Temsirolimus - Torisel
• TEMSIROLIMUS [MI]
• TEMSIROLIMUS [INN]
• TEMSIROLIMUS [JAN]
• TEMSIROLIMUS [VANDF]
• UNII-624KN6GM2T
• SCHEMBL18792
• TEMSIROLIMUS [MART.]
• 42-(3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate)rapamycin