← SynDRA

DIPHENOXYLATE

SynDRA canonical compound SYN0023521 — structure-anchored drug synonym record

All known targets

• OPRM1
• KCNA3

Mechanisms of action (all sources)

• Opioid receptor agonist
• OPRM1 AGONIST
• Mu opioid receptor agonist

Drug classes

• Analgesics
• Analgesics, Opioid
• Antidiarrheals
• Central Nervous System Agents
• Central Nervous System Depressants
• Gastrointestinal Agents
• Narcotics
• Peripheral Nervous System Agents
• Sensory System Agents
• Antidiarrheal

ATC classes

• A07D · ANTIPROPULSIVES

Cross-references

• PubChem CID: 13505
• ChEMBL: CHEMBL1201294
• DrugBank: DB01081
• ChEBI: CHEBI:4639
• KEGG: D03860
• RxNorm: 3500
• Wikipedia: Diphenoxylate
• TTD: D0J2TN
• LINCS BRD: BRD-K41903098

Synonyms

• diphenoxylate hydrochloride
• diphenoxylate HCl
• Difenoxilato
• IDS-ND-016
• Difenossilato
• Diphenoxalate
• Diphenoxylatum
• Difenossilato [DCIT]
• Difenoxilato [Spanish]
• Diphenoxylate HCl
• Diphenoxylate Monohydrochloride
• Diphenoxylate hydrochloride
• Diphenoxylatum [Latin]
• NIH 7562
• R-1132
• Difenoxilato [INN-Spanish]
• Diphenoxylate (INN)
• Diphenoxylate [INN:BAN]
• Diphenoxylate hydrochloride (USP)
• Diphenoxylate hydrochloride(usp)
• Diphenoxylatum [INN-Latin]
• R 1132 (antiperistaltic)
• Co-phenotrope (TN)
• Ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenylisonipecotate
• Ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenylisonipecotate monohydrochloride
• Ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-4-piperidinecarboxylate
• Ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylate
• Ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylate hydrochloride
• Isonipecotic acid, 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-, ethyl ester
• Ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidin-1-ium-4-carboxylate chloride
• Isonipecotic acid, 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-, ethyl ester, hydrochloride
• 1-(3-Cyano-3,3-diphenylpropyl)-4-phenyl-4-piperidinecarboxylic acid ethyl ester
• 1-(3-Cyano-3,3-diphenylpropyl)-4-phenyl-isonipecotic acid ethyl ester
• 1-(3-Cyano-3,3-diphenylpropyl)-4-phenylisonipecotic acid ethyl ester hydrochloride
• 1-(3-cyano-3,3-diphenylpropyl)-4-(ethoxycarbonyl)-4-phenylpiperidinium chloride
• 2,2-Diphenyl-4-(4-carbethoxy-4-phenylpiperidino)butyronitrile
• 4-Ethoxycarbonyl-alpha,alpha,4-triphenyl-1-piperidinebutyronitrile, hydrochloride
• 4-Piperidinecarboxylic acid, 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-, ethyl ester

Reported adverse events

• Dehydration